TY - JOUR
T1 - Percutaneous Repair of Mitral Regurgitation
T2 - A Comprehensive Review of Literature
AU - Salehin, Salman
AU - Hasan, Syed Mustajab
AU - Mai, Steven
AU - Rasmussen, Peter
AU - Shahzad, Ahmad
AU - Abdelmaseih, Ramy
AU - Jazar, Deaa Abu
AU - Shalaby, Mostafa
AU - Motiwala, Afaq
AU - Gilani, Syed
AU - Khalife, Wissam I.
N1 - Publisher Copyright:
© 2022 Elsevier Inc.
PY - 2022/11
Y1 - 2022/11
N2 - Mitral regurgitation is the most common valvular disease in the US and the second most common worldwide. Left untreated, it can lead to the development of heart failure, giving rise to increased mortality rates. Mitral valve intervention is usually indicated in severe mitral regurgitation at the onset of symptoms, even if the function of the left ventricle is preserved. A surgical approach is generally favored according to current guidelines, with excellent clinical outcomes. However, the emergence of novel data from contemporary trials indicates that percutaneous, catheter-based approach may have similar improvements in mortality outcomes while maintaining a superior safety profile when compared to the surgical approach. Here, we discuss transcatheter mitral valve repair as a treatment option for mitral regurgitation and summarize the major clinical trials which were recently conducted on transcatheter repair.
AB - Mitral regurgitation is the most common valvular disease in the US and the second most common worldwide. Left untreated, it can lead to the development of heart failure, giving rise to increased mortality rates. Mitral valve intervention is usually indicated in severe mitral regurgitation at the onset of symptoms, even if the function of the left ventricle is preserved. A surgical approach is generally favored according to current guidelines, with excellent clinical outcomes. However, the emergence of novel data from contemporary trials indicates that percutaneous, catheter-based approach may have similar improvements in mortality outcomes while maintaining a superior safety profile when compared to the surgical approach. Here, we discuss transcatheter mitral valve repair as a treatment option for mitral regurgitation and summarize the major clinical trials which were recently conducted on transcatheter repair.
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U2 - 10.1016/j.cpcardiol.2022.101338
DO - 10.1016/j.cpcardiol.2022.101338
M3 - Review article
C2 - 35872053
AN - SCOPUS:85137077174
SN - 0146-2806
VL - 47
JO - Current Problems in Cardiology
JF - Current Problems in Cardiology
IS - 11
M1 - 101338
ER -