TY - JOUR
T1 - Pathology of the pleura
T2 - What the pulmonologists need to know
AU - Cagle, Philip T.
AU - Allen, Timothy Craig
N1 - Copyright:
Copyright 2011 Elsevier B.V., All rights reserved.
PY - 2011/4
Y1 - 2011/4
N2 - Primary and metastatic pleural neoplasms, and nonneoplastic pleural diseases, can have similar clinical, radiographic and gross features. However, treatments and prognoses of these diverse pleural conditions vary greatly. Accurate diagnosis of pleural disease is therefore extremely important, and histological interpretation of pleural biopsies is vital to rendering an accurate diagnosis. Smaller biopsies contribute to the difficulties in accurately characterizing pleural lesions, and immunostains are frequently employed in their assessment. Diffuse malignant mesothelioma, the most common primary pulmonary neoplasm, is rare; however, other less common primary pleural neoplasms, including solitary fibrous tumour, the most common benign primary pleural neoplasm, occur. These neoplasms are discussed. Also, non-neoplastic pleural diseases, including granulomatous pleuritis, eosinophilic pleuritis and fibrous and fibrinous pleuritis, among other diseases, are discussed.
AB - Primary and metastatic pleural neoplasms, and nonneoplastic pleural diseases, can have similar clinical, radiographic and gross features. However, treatments and prognoses of these diverse pleural conditions vary greatly. Accurate diagnosis of pleural disease is therefore extremely important, and histological interpretation of pleural biopsies is vital to rendering an accurate diagnosis. Smaller biopsies contribute to the difficulties in accurately characterizing pleural lesions, and immunostains are frequently employed in their assessment. Diffuse malignant mesothelioma, the most common primary pulmonary neoplasm, is rare; however, other less common primary pleural neoplasms, including solitary fibrous tumour, the most common benign primary pleural neoplasm, occur. These neoplasms are discussed. Also, non-neoplastic pleural diseases, including granulomatous pleuritis, eosinophilic pleuritis and fibrous and fibrinous pleuritis, among other diseases, are discussed.
KW - Atypical mesothelial cell hyperplasia
KW - Mesothelioma
KW - Pleura
KW - Pleuritis
KW - Solitary fibrous tumour
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U2 - 10.1111/j.1440-1843.2011.01957.x
DO - 10.1111/j.1440-1843.2011.01957.x
M3 - Review article
C2 - 21362105
AN - SCOPUS:79953275625
SN - 1323-7799
VL - 16
SP - 430
EP - 438
JO - Respirology
JF - Respirology
IS - 3
ER -