Pathogenesis and Clinical and Economic Consequences of Postoperative Ileus

Michael G. Doorly, Anthony J. Senagore

Research output: Contribution to journalReview articlepeer-review

53 Scopus citations


Postoperative ileus is a preventable disease with surprising economic consequences. Understanding the triad of dysmotility in conjunction with an enhanced recovery program improves patient outcome, decreases length of stay in hospital, and lowers the cost. Alvimopan and other investigational promotility medications can help attain these goals. Surgeons should avoid labeling all postoperative abdominal distention as ileus, which not only prevents timely diagnosis and treatment of early postoperative small bowel obstruction or acute colonic pseudo-obstruction but also increases patient morbidity and mortality.

Original languageEnglish (US)
Pages (from-to)259-272
Number of pages14
JournalSurgical Clinics of North America
Issue number2
StatePublished - Apr 2012
Externally publishedYes


  • Abdominal surgery
  • Alvimopan
  • Early postoperative small bowel obstruction
  • Ogilvie syndrome
  • Postoperative ileus

ASJC Scopus subject areas

  • Surgery


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