Patency and limb salvage for polytetrafluoroethylene bypasses with vein interposition cuffs

Nikhil Kansal, Peter J. Pappas, Gary A. Gwertzman, Michael B. Silva, Zafar Jamil, Bing C. Lee, Florence Chan, Frank T. Padberg, Robert W. Hobson

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


Polytetrafluoroethelene (PTFE) is often utilized in patients with limb- threatening ischemia requiring infrainguinal revascularization in the absence of autologous saphenous vein. To increase long-term patency of PTFE grafts, vein interposition cuffs have been recommended as adjunctive procedures. The purpose of this study was to assess the efficacy of vein interposition cuffs on the long-term patency and limb salvage of patients requiring prosthetic bypass grafts for limb-threatening ischemia. Prosthetic bypass grafts with vein interposition cuffs (PTFE/VC) were performed on 56 limbs in 55 patients (32 men, 23 women; mean age of 67 years) from October 1993 to January 1998. Grafts were prospectively evaluated every 3 months for the first 12 months and biannually thereafter with duplex ultrasonography. PTFE/VC and PTFE bypasses at the popliteal level appear to have comparable patencies. However, PTFE/VC appear to offer an improved patency and limb salvage for infrapopliteal bypasses in patients with critical limb ischemia. When infrapopliteal revascularization is required in the absence of autologous saphenous vein, we recommend the use of PTFE with vein interposition cuffs.

Original languageEnglish (US)
Pages (from-to)386-392
Number of pages7
JournalAnnals of Vascular Surgery
Issue number4
StatePublished - 1999
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Cardiology and Cardiovascular Medicine


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