TY - JOUR
T1 - Past, Present, and Future of Pharmacologic Therapy in Obesity
AU - Rodríguez, José E.
AU - Campbell, Kendall M.
N1 - Publisher Copyright:
© 2016 Elsevier Inc.
PY - 2016/3/1
Y1 - 2016/3/1
N2 - Medications for obesity management can be divided into 4 groups: antidepressants (naltrexone/bupropion), stimulants (phentermine, phendimetrazine, diethylpropion, phentermine/topiramate), fat blockers (orlistat), and diabetes medications (liraglutide). Each group has specific therapeutic effects, adverse effects, and costs. Two medications are indicated for long-term use in obesity: lorcaserin and orlistat. Other available medications are for short-term use. High cost makes many of these medications inaccessible for underserved and poor patients. Because of misuse potential, many obesity medications are also classified as controlled substances. There are no medications currently approved for use in pregnant or lactating women.
AB - Medications for obesity management can be divided into 4 groups: antidepressants (naltrexone/bupropion), stimulants (phentermine, phendimetrazine, diethylpropion, phentermine/topiramate), fat blockers (orlistat), and diabetes medications (liraglutide). Each group has specific therapeutic effects, adverse effects, and costs. Two medications are indicated for long-term use in obesity: lorcaserin and orlistat. Other available medications are for short-term use. High cost makes many of these medications inaccessible for underserved and poor patients. Because of misuse potential, many obesity medications are also classified as controlled substances. There are no medications currently approved for use in pregnant or lactating women.
KW - Antidepressants
KW - Fat blockers
KW - Obesity
KW - Pharmacology treatment
KW - Stimulants
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U2 - 10.1016/j.pop.2015.08.011
DO - 10.1016/j.pop.2015.08.011
M3 - Review article
C2 - 26896200
AN - SCOPUS:84958116797
SN - 0095-4543
VL - 43
SP - 61
EP - 67
JO - Primary Care - Clinics in Office Practice
JF - Primary Care - Clinics in Office Practice
IS - 1
ER -