Optimized production and immunogenicity of an insect virus-based chikungunya virus candidate vaccine in cell culture and animal models

Immunology and Microbiology

• Animal 100%
• Vaccine Efficacy 100%
• Chikungunya Virus 100%
• Immunogenicity 100%
• Cell Culture 100%
• Insect Virus 100%
• Mouse 66%
• Cells 66%
• Dose 66%
• Adaptive Immune System 66%
• Virus 66%
• Cytotoxic T-Cell 66%
• Memory B Cell 66%
• Mosquito 33%
• Sensitization 33%
• Immunity 33%
• Innate Immune System 33%
• CD8 33%
• Antigen Presenting Cell 33%
• Kinetics 33%
• T-Helper Cell 33%
• Immunoglobulin M Antibody 33%
• Immunoglobulin G Antibody 33%
• Cytokine Response 33%
• Antigen-Presenting Cell 33%

INIS

• production 100%
• vaccines 100%
• insects 100%
• viruses 100%
• cell cultures 100%
• cells (animal) 100%
• immunity 60%
• mice 40%
• levels 40%
• doses 40%
• antibodies 20%
• antigens 20%
• in vivo 20%
• in vitro 20%
• animals 20%
• mosquitoes 20%
• comparative evaluations 20%
• induction 20%
• cytokines 20%
• strains 20%
• stocks 20%
• kinetics 20%

Keyphrases

• Optimized Production 100%
• Eilat 8%
• Robust Adaptive 8%
• Sensitization Study 8%