Normal F-18 FDG vertebral uptake in Paget's disease on PET scanning

Peeyush Bhargava; Marsha Naydich; Munir Ghesani

doi:10.1097/00003072-200503000-00012

Normal F-18 FDG vertebral uptake in Paget's disease on PET scanning

Peeyush Bhargava, Marsha Naydich, Munir Ghesani

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Whole-body bone scans remain the standard of care in the management of patients with suspected bone metastases. They are very sensitive for bone disease but are nonspecific. Various benign bone pathologies can give rise to foci of increased activity, which may mimic osteoblastic bone metastases. Whole-body PET with FDG has been shown to be of great value for the evaluation of bone metastases, with high sensitivity and specificity. This case shows normal FDG activity in a vertebra affected by Paget's disease and intense osteoblastic activity on the bone scan, a false-positive finding in the evaluation of suspected skeletal metastases.

Original language	English (US)
Pages (from-to)	191-192
Number of pages	2
Journal	Clinical Nuclear Medicine
Volume	30
Issue number	3
DOIs	https://doi.org/10.1097/00003072-200503000-00012
State	Published - Mar 2005
Externally published	Yes

Keywords

Bone scan
FDG PET
Paget's disease

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1097/00003072-200503000-00012

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title = "Normal F-18 FDG vertebral uptake in Paget's disease on PET scanning",

abstract = "Whole-body bone scans remain the standard of care in the management of patients with suspected bone metastases. They are very sensitive for bone disease but are nonspecific. Various benign bone pathologies can give rise to foci of increased activity, which may mimic osteoblastic bone metastases. Whole-body PET with FDG has been shown to be of great value for the evaluation of bone metastases, with high sensitivity and specificity. This case shows normal FDG activity in a vertebra affected by Paget's disease and intense osteoblastic activity on the bone scan, a false-positive finding in the evaluation of suspected skeletal metastases.",

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AU - Naydich, Marsha

AU - Ghesani, Munir

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Y1 - 2005/3

N2 - Whole-body bone scans remain the standard of care in the management of patients with suspected bone metastases. They are very sensitive for bone disease but are nonspecific. Various benign bone pathologies can give rise to foci of increased activity, which may mimic osteoblastic bone metastases. Whole-body PET with FDG has been shown to be of great value for the evaluation of bone metastases, with high sensitivity and specificity. This case shows normal FDG activity in a vertebra affected by Paget's disease and intense osteoblastic activity on the bone scan, a false-positive finding in the evaluation of suspected skeletal metastases.

AB - Whole-body bone scans remain the standard of care in the management of patients with suspected bone metastases. They are very sensitive for bone disease but are nonspecific. Various benign bone pathologies can give rise to foci of increased activity, which may mimic osteoblastic bone metastases. Whole-body PET with FDG has been shown to be of great value for the evaluation of bone metastases, with high sensitivity and specificity. This case shows normal FDG activity in a vertebra affected by Paget's disease and intense osteoblastic activity on the bone scan, a false-positive finding in the evaluation of suspected skeletal metastases.

KW - Bone scan

KW - FDG PET

KW - Paget's disease

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Normal F-18 FDG vertebral uptake in Paget's disease on PET scanning

Abstract

Keywords

ASJC Scopus subject areas

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