Nipah virus outbreak with person-to-person transmission in a district of Bangladesh, 2007

N. Homaira; M. Rahman; M. J. Hossain; J. H. Epstein; R. Sultana; M. S.U. Khan; G. Podder; K. Nahar; B. Ahmed; E. S. Gurley; P. Daszak; W. I. Lipkin; P. E. Rollin; J. A. Comer; T. G. Ksiazek; S. P. Luby

doi:10.1017/S0950268810000695

Nipah virus outbreak with person-to-person transmission in a district of Bangladesh, 2007

N. Homaira, M. Rahman, M. J. Hossain, J. H. Epstein, R. Sultana, M. S.U. Khan, G. Podder, K. Nahar, B. Ahmed, E. S. Gurley, P. Daszak, W. I. Lipkin, P. E. Rollin, J. A. Comer, T. G. Ksiazek, S. P. Luby

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100 Scopus citations

Abstract

In February 2007 an outbreak of Nipah virus (NiV) encephalitis in Thakurgaon District of northwest Bangladesh affected seven people, three of whom died. All subsequent cases developed illness 7-14 days after close physical contact with the index case while he was ill. Cases were more likely than controls to have been in the same room (100% vs. 95%, OR undefined, P<0001) and to have touched him (83% vs. 0%, OR undefined, P<0001). Although the source of infection for the index case was not identified, 50% of Pteropus bats sampled from near the outbreak area 1 month after the outbreak had antibodies to NiV confirming the presence of the virus in the area. The outbreak was spread by person-to-person transmission. Risk of NiV infection in family caregivers highlights the need for infection control practices to limit transmission of potentially infectious body secretions.

Original language	English (US)
Pages (from-to)	1630-1636
Number of pages	7
Journal	Epidemiology and infection
Volume	138
Issue number	11
DOIs	https://doi.org/10.1017/S0950268810000695
State	Published - Nov 2010
Externally published	Yes

Keywords

Bangladesh
Nipah virus
person-to-person transmission

ASJC Scopus subject areas

Epidemiology
Infectious Diseases

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10.1017/S0950268810000695

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Homaira, N., Rahman, M., Hossain, M. J., Epstein, J. H., Sultana, R., Khan, M. S. U., Podder, G., Nahar, K., Ahmed, B., Gurley, E. S., Daszak, P., Lipkin, W. I., Rollin, P. E., Comer, J. A., Ksiazek, T. G., & Luby, S. P. (2010). Nipah virus outbreak with person-to-person transmission in a district of Bangladesh, 2007. Epidemiology and infection, 138(11), 1630-1636. https://doi.org/10.1017/S0950268810000695

Homaira, N, Rahman, M, Hossain, MJ, Epstein, JH, Sultana, R, Khan, MSU, Podder, G, Nahar, K, Ahmed, B, Gurley, ES, Daszak, P, Lipkin, WI, Rollin, PE, Comer, JA, Ksiazek, TG & Luby, SP 2010, 'Nipah virus outbreak with person-to-person transmission in a district of Bangladesh, 2007', Epidemiology and infection, vol. 138, no. 11, pp. 1630-1636. https://doi.org/10.1017/S0950268810000695

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title = "Nipah virus outbreak with person-to-person transmission in a district of Bangladesh, 2007",

abstract = "In February 2007 an outbreak of Nipah virus (NiV) encephalitis in Thakurgaon District of northwest Bangladesh affected seven people, three of whom died. All subsequent cases developed illness 7-14 days after close physical contact with the index case while he was ill. Cases were more likely than controls to have been in the same room (100% vs. 95%, OR undefined, P<0001) and to have touched him (83% vs. 0%, OR undefined, P<0001). Although the source of infection for the index case was not identified, 50% of Pteropus bats sampled from near the outbreak area 1 month after the outbreak had antibodies to NiV confirming the presence of the virus in the area. The outbreak was spread by person-to-person transmission. Risk of NiV infection in family caregivers highlights the need for infection control practices to limit transmission of potentially infectious body secretions.",

keywords = "Bangladesh, Nipah virus, person-to-person transmission",

author = "N. Homaira and M. Rahman and Hossain, {M. J.} and Epstein, {J. H.} and R. Sultana and Khan, {M. S.U.} and G. Podder and K. Nahar and B. Ahmed and Gurley, {E. S.} and P. Daszak and Lipkin, {W. I.} and Rollin, {P. E.} and Comer, {J. A.} and Ksiazek, {T. G.} and Luby, {S. P.}",

year = "2010",

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doi = "10.1017/S0950268810000695",

language = "English (US)",

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AU - Hossain, M. J.

AU - Epstein, J. H.

AU - Sultana, R.

AU - Khan, M. S.U.

AU - Podder, G.

AU - Nahar, K.

AU - Ahmed, B.

AU - Gurley, E. S.

AU - Daszak, P.

AU - Lipkin, W. I.

AU - Rollin, P. E.

AU - Comer, J. A.

AU - Ksiazek, T. G.

AU - Luby, S. P.

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N2 - In February 2007 an outbreak of Nipah virus (NiV) encephalitis in Thakurgaon District of northwest Bangladesh affected seven people, three of whom died. All subsequent cases developed illness 7-14 days after close physical contact with the index case while he was ill. Cases were more likely than controls to have been in the same room (100% vs. 95%, OR undefined, P<0001) and to have touched him (83% vs. 0%, OR undefined, P<0001). Although the source of infection for the index case was not identified, 50% of Pteropus bats sampled from near the outbreak area 1 month after the outbreak had antibodies to NiV confirming the presence of the virus in the area. The outbreak was spread by person-to-person transmission. Risk of NiV infection in family caregivers highlights the need for infection control practices to limit transmission of potentially infectious body secretions.

AB - In February 2007 an outbreak of Nipah virus (NiV) encephalitis in Thakurgaon District of northwest Bangladesh affected seven people, three of whom died. All subsequent cases developed illness 7-14 days after close physical contact with the index case while he was ill. Cases were more likely than controls to have been in the same room (100% vs. 95%, OR undefined, P<0001) and to have touched him (83% vs. 0%, OR undefined, P<0001). Although the source of infection for the index case was not identified, 50% of Pteropus bats sampled from near the outbreak area 1 month after the outbreak had antibodies to NiV confirming the presence of the virus in the area. The outbreak was spread by person-to-person transmission. Risk of NiV infection in family caregivers highlights the need for infection control practices to limit transmission of potentially infectious body secretions.

KW - Bangladesh

KW - Nipah virus

KW - person-to-person transmission

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Nipah virus outbreak with person-to-person transmission in a district of Bangladesh, 2007

Abstract

Keywords

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