Neuropsychiatric Symptoms by Cognitive Status for Mexican-Americans Aged 85 and Older

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Few studies have investigated the relationship between neuropsychiatric symptoms (NPS) and cognitive status among older Mexican-American adults. Our objective was to describe the NPS of Mexican-Americans 85 years and older according to cognitive status. Data came from Wave 9 (conducted in 2016) of the Hispanic Established Populations for the Epidemiological Study of the Elderly. The final sample consisted of 381 care recipients ≥85 years. The 12-item Neuropsychiatric Inventory was administered to measure NPS among care recipients. Cognitive impairment was defined as a score of ≤18 on the Mini Mental State Exam or by clinical diagnosis of dementia as reported by the caregiver. Logistic regression models were used to estimate the average marginal effect (range = –1 to 1) of cognitive impairment on NPS, controlling for care-recipient characteristics. Overall, 259 (68.0%) participants had one or more NPS. Approximately 87% of care recipients with cognitive impairment had at least one NPS compared to 55.8% of those without cognitive impairment (p <.01). The predicted probability of having one or more NPS was 0.25% points (95% CI = 0.14–0.35) higher for participants with cognitive impairment than those without. NPS are present in the majority of very old Mexican American adults, particularly in those with cognitive impairment.

Original languageEnglish (US)
JournalGerontology and Geriatric Medicine
StatePublished - 2021


  • Mexican-Americans
  • cognitive impairment
  • neuropsychiatric inventory
  • neuropsychiatric symptoms

ASJC Scopus subject areas

  • Geriatrics and Gerontology


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