Necrotizing pancreatitis: Challenges and solutions

Victoria A. Bendersky; Mohan K. Mallipeddi; Alexander Perez; Theodore N. Pappas

doi:10.2147/CEG.S99824

Necrotizing pancreatitis: Challenges and solutions

Victoria A. Bendersky, Mohan K. Mallipeddi, Alexander Perez, Theodore N. Pappas

Research output: Contribution to journal › Review article › peer-review

8 Scopus citations

Abstract

Acute pancreatitis is a common disease that can progress to gland necrosis, which imposes significant risk of morbidity and mortality. In general, the treatment for pancreatitis is a supportive therapy. However, there are several reasons to escalate to surgery or another intervention. This review discusses the pathophysiology as well as medical and interventional management of necrotizing pancreatitis. Current evidence suggests that patients are best served by delaying interventions for at least 4 weeks, draining as a first resort, and debriding recalcitrant tissue using minimally invasive techniques to promote or enhance postoperative recovery while reducing wound-related complications.

Original language	English (US)
Pages (from-to)	345-350
Number of pages	6
Journal	Clinical and Experimental Gastroenterology
Volume	9
DOIs	https://doi.org/10.2147/CEG.S99824
State	Published - Oct 31 2016
Externally published	Yes

Keywords

Necrotizing pancreatitis
Pancreatic collections
Pancreatic debridement
Pancreatic necrosectomy
VARD

ASJC Scopus subject areas

Gastroenterology

Access to Document

10.2147/CEG.S99824

Cite this

@article{35996fcb111944de854394cfc5f3e1ba,

title = "Necrotizing pancreatitis: Challenges and solutions",

abstract = "Acute pancreatitis is a common disease that can progress to gland necrosis, which imposes significant risk of morbidity and mortality. In general, the treatment for pancreatitis is a supportive therapy. However, there are several reasons to escalate to surgery or another intervention. This review discusses the pathophysiology as well as medical and interventional management of necrotizing pancreatitis. Current evidence suggests that patients are best served by delaying interventions for at least 4 weeks, draining as a first resort, and debriding recalcitrant tissue using minimally invasive techniques to promote or enhance postoperative recovery while reducing wound-related complications.",

keywords = "Necrotizing pancreatitis, Pancreatic collections, Pancreatic debridement, Pancreatic necrosectomy, VARD",

author = "Bendersky, {Victoria A.} and Mallipeddi, {Mohan K.} and Alexander Perez and Pappas, {Theodore N.}",

note = "Publisher Copyright: {\textcopyright} 2016 Bendersky et al.",

year = "2016",

month = oct,

day = "31",

doi = "10.2147/CEG.S99824",

language = "English (US)",

volume = "9",

pages = "345--350",

journal = "Clinical and Experimental Gastroenterology",

issn = "1178-7023",

publisher = "Dove Medical Press Ltd.",

}

TY - JOUR

T1 - Necrotizing pancreatitis

T2 - Challenges and solutions

AU - Bendersky, Victoria A.

AU - Mallipeddi, Mohan K.

AU - Perez, Alexander

AU - Pappas, Theodore N.

PY - 2016/10/31

Y1 - 2016/10/31

N2 - Acute pancreatitis is a common disease that can progress to gland necrosis, which imposes significant risk of morbidity and mortality. In general, the treatment for pancreatitis is a supportive therapy. However, there are several reasons to escalate to surgery or another intervention. This review discusses the pathophysiology as well as medical and interventional management of necrotizing pancreatitis. Current evidence suggests that patients are best served by delaying interventions for at least 4 weeks, draining as a first resort, and debriding recalcitrant tissue using minimally invasive techniques to promote or enhance postoperative recovery while reducing wound-related complications.

AB - Acute pancreatitis is a common disease that can progress to gland necrosis, which imposes significant risk of morbidity and mortality. In general, the treatment for pancreatitis is a supportive therapy. However, there are several reasons to escalate to surgery or another intervention. This review discusses the pathophysiology as well as medical and interventional management of necrotizing pancreatitis. Current evidence suggests that patients are best served by delaying interventions for at least 4 weeks, draining as a first resort, and debriding recalcitrant tissue using minimally invasive techniques to promote or enhance postoperative recovery while reducing wound-related complications.

KW - Necrotizing pancreatitis

KW - Pancreatic collections

KW - Pancreatic debridement

KW - Pancreatic necrosectomy

KW - VARD

UR - http://www.scopus.com/inward/record.url?scp=84995553794&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84995553794&partnerID=8YFLogxK

U2 - 10.2147/CEG.S99824

DO - 10.2147/CEG.S99824

M3 - Review article

AN - SCOPUS:84995553794

SN - 1178-7023

VL - 9

SP - 345

EP - 350

JO - Clinical and Experimental Gastroenterology

JF - Clinical and Experimental Gastroenterology

ER -

Necrotizing pancreatitis: Challenges and solutions

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this