Multiple site analytical evaluation of a portable blood gas/electrolyte analyzer for point of care testing

Jeffrey J. Chance; Dai J. Li; Lori J. Sokoll; Mark A. Silberman; Mike E. Engelstad; James H. Nichols; Xuhui Liu; Amin A. Mohammad; John R. Petersen; Anthony O. Okorodudu

doi:10.1097/00003246-200006000-00069

Multiple site analytical evaluation of a portable blood gas/electrolyte analyzer for point of care testing

Jeffrey J. Chance, Dai J. Li, Lori J. Sokoll, Mark A. Silberman, Mike E. Engelstad, James H. Nichols, Xuhui Liu, Amin A. Mohammad, John R. Petersen, Anthony O. Okorodudu

Pathology

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Objective: To evaluate the analytical performance of the SenDx 100 portable blood gas and electrolyte analyzer (SenDx Medical, Carlsbad, CA). Design: Accuracy was evaluated by correlation of whole blood patient samples with the Nova Stat Profile 5 (Nova Biomedical, Waltham, MA) and the Ciba Corning 865 (Chiron Diagnostics, Medford, MA). Precision was evaluated using quality control materials (RNA Medical, Acton, MA). Setting: Critical care laboratories and operating rooms in two institutions. Measurements and Main Results: Precision studies performed at three different concentration levels for each analyte demonstrated intra-assay precision of ≤2.5% coefficient of variation and interassay precision of ≤4.0% coefficient of variation in all cases. Analysis of patient specimens in general showed good to excellent correlation to reference analyzers. Regression variables are tabulated. Conclusions: The SenDx 100 portable blood gas and electrolyte analyzer is a simple and easy to use analyzer demonstrating acceptable performance compared with reference methods.

Original language	English (US)
Pages (from-to)	2081-2085
Number of pages	5
Journal	Critical care medicine
Volume	28
Issue number	6
DOIs	https://doi.org/10.1097/00003246-200006000-00069
State	Published - 2000

Keywords

Blood gases
Correlation
Cost
Critical care medicine
Electrolytes
Point of care testing
Portable
Tonometry

ASJC Scopus subject areas

Critical Care and Intensive Care Medicine

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10.1097/00003246-200006000-00069

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@article{28a238f8340046319643ca310a8d7dd9,

title = "Multiple site analytical evaluation of a portable blood gas/electrolyte analyzer for point of care testing",

abstract = "Objective: To evaluate the analytical performance of the SenDx 100 portable blood gas and electrolyte analyzer (SenDx Medical, Carlsbad, CA). Design: Accuracy was evaluated by correlation of whole blood patient samples with the Nova Stat Profile 5 (Nova Biomedical, Waltham, MA) and the Ciba Corning 865 (Chiron Diagnostics, Medford, MA). Precision was evaluated using quality control materials (RNA Medical, Acton, MA). Setting: Critical care laboratories and operating rooms in two institutions. Measurements and Main Results: Precision studies performed at three different concentration levels for each analyte demonstrated intra-assay precision of ≤2.5% coefficient of variation and interassay precision of ≤4.0% coefficient of variation in all cases. Analysis of patient specimens in general showed good to excellent correlation to reference analyzers. Regression variables are tabulated. Conclusions: The SenDx 100 portable blood gas and electrolyte analyzer is a simple and easy to use analyzer demonstrating acceptable performance compared with reference methods.",

keywords = "Blood gases, Correlation, Cost, Critical care medicine, Electrolytes, Point of care testing, Portable, Tonometry",

author = "Chance, {Jeffrey J.} and Li, {Dai J.} and Sokoll, {Lori J.} and Silberman, {Mark A.} and Engelstad, {Mike E.} and Nichols, {James H.} and Xuhui Liu and Mohammad, {Amin A.} and Petersen, {John R.} and Okorodudu, {Anthony O.}",

year = "2000",

doi = "10.1097/00003246-200006000-00069",

language = "English (US)",

volume = "28",

pages = "2081--2085",

journal = "Critical care medicine",

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TY - JOUR

T1 - Multiple site analytical evaluation of a portable blood gas/electrolyte analyzer for point of care testing

AU - Chance, Jeffrey J.

AU - Li, Dai J.

AU - Sokoll, Lori J.

AU - Silberman, Mark A.

AU - Engelstad, Mike E.

AU - Nichols, James H.

AU - Liu, Xuhui

AU - Mohammad, Amin A.

AU - Petersen, John R.

AU - Okorodudu, Anthony O.

PY - 2000

Y1 - 2000

N2 - Objective: To evaluate the analytical performance of the SenDx 100 portable blood gas and electrolyte analyzer (SenDx Medical, Carlsbad, CA). Design: Accuracy was evaluated by correlation of whole blood patient samples with the Nova Stat Profile 5 (Nova Biomedical, Waltham, MA) and the Ciba Corning 865 (Chiron Diagnostics, Medford, MA). Precision was evaluated using quality control materials (RNA Medical, Acton, MA). Setting: Critical care laboratories and operating rooms in two institutions. Measurements and Main Results: Precision studies performed at three different concentration levels for each analyte demonstrated intra-assay precision of ≤2.5% coefficient of variation and interassay precision of ≤4.0% coefficient of variation in all cases. Analysis of patient specimens in general showed good to excellent correlation to reference analyzers. Regression variables are tabulated. Conclusions: The SenDx 100 portable blood gas and electrolyte analyzer is a simple and easy to use analyzer demonstrating acceptable performance compared with reference methods.

AB - Objective: To evaluate the analytical performance of the SenDx 100 portable blood gas and electrolyte analyzer (SenDx Medical, Carlsbad, CA). Design: Accuracy was evaluated by correlation of whole blood patient samples with the Nova Stat Profile 5 (Nova Biomedical, Waltham, MA) and the Ciba Corning 865 (Chiron Diagnostics, Medford, MA). Precision was evaluated using quality control materials (RNA Medical, Acton, MA). Setting: Critical care laboratories and operating rooms in two institutions. Measurements and Main Results: Precision studies performed at three different concentration levels for each analyte demonstrated intra-assay precision of ≤2.5% coefficient of variation and interassay precision of ≤4.0% coefficient of variation in all cases. Analysis of patient specimens in general showed good to excellent correlation to reference analyzers. Regression variables are tabulated. Conclusions: The SenDx 100 portable blood gas and electrolyte analyzer is a simple and easy to use analyzer demonstrating acceptable performance compared with reference methods.

KW - Blood gases

KW - Correlation

KW - Cost

KW - Critical care medicine

KW - Electrolytes

KW - Point of care testing

KW - Portable

KW - Tonometry

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Multiple site analytical evaluation of a portable blood gas/electrolyte analyzer for point of care testing

Abstract

Keywords

ASJC Scopus subject areas

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