Molecular testing in emerging infectious diseases

Jianli Dong; Nahed Ismail; Eric Fitts; David H. Walker

doi:10.1016/B978-0-12-822824-1.00011-0

Molecular testing in emerging infectious diseases

Jianli Dong, Nahed Ismail, Eric Fitts, David H. Walker

Pathology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

It was widely believed in the late 1960s that infectious diseases had been conquered by vaccines and antibiotics and humans were no longer under threat by microbial pathogens. Yet, since that time more than 60 pathogens have been discovered that can cause serious emerging infectious diseases. Molecular methods have played critical roles in the discovery, monitoring, and clinical diagnostics of emerging pathogens. In this chapter, we present well-recognized emerging pathogens. We provide examples of the utility of molecular assays in research and clinical care of emerging infectious diseases. We also discuss some theoretical and practical limitations of molecular tests and the future prospects of expanding molecular diagnostics for emerging pathogens based on new advances in knowledge and technologies.

Original language	English (US)
Title of host publication	Diagnostic Molecular Pathology
Subtitle of host publication	A Guide to Applied Molecular Testing, Second Edition
Publisher	Elsevier
Pages	175-198
Number of pages	24
ISBN (Electronic)	9780128228241
ISBN (Print)	9780128229934
DOIs	https://doi.org/10.1016/B978-0-12-822824-1.00011-0
State	Published - Jan 1 2023

Keywords

emerging infectious diseases and emerging pathogens
Molecular diagnostics
molecular methods
molecular tests

ASJC Scopus subject areas

General Medicine

Access to Document

10.1016/B978-0-12-822824-1.00011-0

Cite this

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AB - It was widely believed in the late 1960s that infectious diseases had been conquered by vaccines and antibiotics and humans were no longer under threat by microbial pathogens. Yet, since that time more than 60 pathogens have been discovered that can cause serious emerging infectious diseases. Molecular methods have played critical roles in the discovery, monitoring, and clinical diagnostics of emerging pathogens. In this chapter, we present well-recognized emerging pathogens. We provide examples of the utility of molecular assays in research and clinical care of emerging infectious diseases. We also discuss some theoretical and practical limitations of molecular tests and the future prospects of expanding molecular diagnostics for emerging pathogens based on new advances in knowledge and technologies.

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ER -

Molecular testing in emerging infectious diseases

Abstract

Keywords

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