Molecular epidemiology of an outbreak of human parainfluenza virus 3 among oncology patients

E. S. Bailey; E. Lobaugh-Jin; B. Smith; C. Sova; J. Misuraca; N. Henshaw; G. C. Gray

doi:10.1016/j.jhin.2019.07.012

Molecular epidemiology of an outbreak of human parainfluenza virus 3 among oncology patients

E. S. Bailey, E. Lobaugh-Jin, B. Smith, C. Sova, J. Misuraca, N. Henshaw, G. C. Gray

Research output: Contribution to journal › Article › peer-review

Abstract

A hospital outbreak of human parainfluenza virus type 3 (HPIV-3) in haematologic oncology patients is described in 12 patients over a four-week period. Exposure histories and molecular analysis of HPIV-3 isolates suggest that both community-acquired and nosocomially transmitted infections occurred during this outbreak. Molecular analysis of HPIV-3 isolates indicated that a chain of transmission occurred among multiple patients in an oncology ward. This transmission was later determined to be associated with the movement of fomites, visitors, and activities in the unit. The infection prevention team stopped nosocomial spread of HPIV-3 through interventions including advanced cleaning procedures.

Original language	English (US)
Pages (from-to)	349-353
Number of pages	5
Journal	Journal of Hospital Infection
Volume	103
Issue number	3
DOIs	https://doi.org/10.1016/j.jhin.2019.07.012
State	Published - Nov 2019
Externally published	Yes

Keywords

Haematology unit
Human parainfluenza virus type 3
Nosocomial outbreak
Phylogenetic analysis

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

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10.1016/j.jhin.2019.07.012

Cite this

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title = "Molecular epidemiology of an outbreak of human parainfluenza virus 3 among oncology patients",

abstract = "A hospital outbreak of human parainfluenza virus type 3 (HPIV-3) in haematologic oncology patients is described in 12 patients over a four-week period. Exposure histories and molecular analysis of HPIV-3 isolates suggest that both community-acquired and nosocomially transmitted infections occurred during this outbreak. Molecular analysis of HPIV-3 isolates indicated that a chain of transmission occurred among multiple patients in an oncology ward. This transmission was later determined to be associated with the movement of fomites, visitors, and activities in the unit. The infection prevention team stopped nosocomial spread of HPIV-3 through interventions including advanced cleaning procedures.",

keywords = "Haematology unit, Human parainfluenza virus type 3, Nosocomial outbreak, Phylogenetic analysis",

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AU - Bailey, E. S.

AU - Lobaugh-Jin, E.

AU - Smith, B.

AU - Sova, C.

AU - Misuraca, J.

AU - Henshaw, N.

AU - Gray, G. C.

PY - 2019/11

Y1 - 2019/11

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AB - A hospital outbreak of human parainfluenza virus type 3 (HPIV-3) in haematologic oncology patients is described in 12 patients over a four-week period. Exposure histories and molecular analysis of HPIV-3 isolates suggest that both community-acquired and nosocomially transmitted infections occurred during this outbreak. Molecular analysis of HPIV-3 isolates indicated that a chain of transmission occurred among multiple patients in an oncology ward. This transmission was later determined to be associated with the movement of fomites, visitors, and activities in the unit. The infection prevention team stopped nosocomial spread of HPIV-3 through interventions including advanced cleaning procedures.

KW - Haematology unit

KW - Human parainfluenza virus type 3

KW - Nosocomial outbreak

KW - Phylogenetic analysis

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Molecular epidemiology of an outbreak of human parainfluenza virus 3 among oncology patients

Abstract

Keywords

ASJC Scopus subject areas

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