Marburg and Ravn Viruses (Filoviridae)

Courtney Woolsey; Thomas W. Geisbert; Robert W. Cross

doi:10.1016/B978-0-12-814515-9.00077-1

Marburg and Ravn Viruses (Filoviridae)

Courtney Woolsey, Thomas W. Geisbert, Robert W. Cross

Microbiology And Immunology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Marburg and Ravn viruses (Family Filoviridae, Order Mononegavirales) cause hemorrhagic disease in humans and non-human primates with clinical manifestations similar to Ebola virus disease. Since its discovery in 1967, MARV has caused infrequent, but deadly, outbreaks mostly within Africa. Its high lethality, bioweapon potential, and endemicity in African bat populations forms a threat to public health. No licensed vaccines or antiviral treatments are currently available.

Original language	English (US)
Title of host publication	Encyclopedia of Virology
Subtitle of host publication	Volume 1-5, Fourth Edition
Publisher	Elsevier
Pages	608-618
Number of pages	11
Volume	1-5
ISBN (Electronic)	9780128145166
DOIs	https://doi.org/10.1016/B978-0-12-814515-9.00077-1
State	Published - Jan 1 2020

Keywords

Classification
Clinical features
Epidemiology
Filoviridae
Filovirus
Genome
Life cycle
Marburg virus
Mononegavirales
Pathogenesis
Therapeutics
Vaccines
Viral hemorrhagic fever
Virus structure

ASJC Scopus subject areas

General Immunology and Microbiology

Access to Document

10.1016/B978-0-12-814515-9.00077-1

Cite this

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AU - Cross, Robert W.

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AB - Marburg and Ravn viruses (Family Filoviridae, Order Mononegavirales) cause hemorrhagic disease in humans and non-human primates with clinical manifestations similar to Ebola virus disease. Since its discovery in 1967, MARV has caused infrequent, but deadly, outbreaks mostly within Africa. Its high lethality, bioweapon potential, and endemicity in African bat populations forms a threat to public health. No licensed vaccines or antiviral treatments are currently available.

KW - Classification

KW - Clinical features

KW - Epidemiology

KW - Filoviridae

KW - Filovirus

KW - Genome

KW - Life cycle

KW - Marburg virus

KW - Mononegavirales

KW - Pathogenesis

KW - Therapeutics

KW - Vaccines

KW - Viral hemorrhagic fever

KW - Virus structure

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ER -

Marburg and Ravn Viruses (Filoviridae)

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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