Long‐term colchicine administration leading to colchicine toxicity and death

Michael N. Neuss; Rex M. McCallum; Wayne D. Brenckman; Harold R. Silberman

doi:10.1002/art.1780290324

Long‐term colchicine administration leading to colchicine toxicity and death

Michael N. Neuss, Rex M. McCallum, Wayne D. Brenckman, Harold R. Silberman

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31 Scopus citations

Abstract

Extracts from the Colchicum autumnale plant have been used to treat gout since the sixth century, and many instances of accidental or intentional overdose have been reported. Although a clinical syndrome due to acute colchicine intoxication is wellknown, we know of no reports of its occurrence while a patient was taking usual prophylactic doses. The following case study may be the first reported example of such an event.

Original language	English (US)
Pages (from-to)	448-449
Number of pages	2
Journal	Arthritis & Rheumatism
Volume	29
Issue number	3
DOIs	https://doi.org/10.1002/art.1780290324
State	Published - Mar 1986
Externally published	Yes

ASJC Scopus subject areas

Immunology and Allergy
Rheumatology
Immunology
Pharmacology (medical)

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abstract = "Extracts from the Colchicum autumnale plant have been used to treat gout since the sixth century, and many instances of accidental or intentional overdose have been reported. Although a clinical syndrome due to acute colchicine intoxication is wellknown, we know of no reports of its occurrence while a patient was taking usual prophylactic doses. The following case study may be the first reported example of such an event.",

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Long‐term colchicine administration leading to colchicine toxicity and death

Abstract

ASJC Scopus subject areas

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