Localized nasopharyngeal amyloidosis: A case report

Jimmy George, Hasan Khan, Irfan Masood, Zahra Akhtar

Research output: Contribution to journalArticlepeer-review


Amyloidosis is a rare condition on its own but finding localized amyloidosis of a site such as the nasopharynx is an extremely rare condition with very few cases described in the literature. The condition occurs due to the accumulation of misfolded proteins in the extracellular space disrupting the cell architecture and causing eventual dysfunction. In this case report we discuss the pathophysiology, symptoms, and imaging findings of a patient initially thought to have giant cell arteritis, but who was found on CT to have a mass later determined to be localized nasopharyngeal amyloidosis. Evaluation will require biopsy as it is the gold standard, but there are many other tests and even reasons to consider the use of interventional radiology to sample other tissues rather than the primary target site for amyloid deposition in conjunction with nuclear imaging.

Original languageEnglish (US)
Pages (from-to)4506-4509
Number of pages4
JournalRadiology Case Reports
Issue number12
StatePublished - Dec 2022


  • Amyloidosis
  • Biopsy
  • Cross-section
  • Diagnostic radiology
  • Interventional radiology
  • Nasopharynx

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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