Lassa virus, but not highly pathogenic new world arenaviruses, restricts immunostimulatory double-stranded RNA accumulation during infection

Keyphrases

• Highly Pathogenic 100%
• Immunostimulatory 100%
• Double-stranded RNA 100%
• New World Arenavirus 100%
• RNA Accumulation 100%
• Lassa Virus 100%
• Nucleoprotein 75%
• Virus 50%
• Exoribonuclease 43%
• Arenavirus 37%
• Virus Infection 31%
• Machupo Virus 31%
• Interferon Response 25%
• Innate Immune Response 18%
• L Protein 18%
• RNA Sensors 18%
• Danger Signals 12%
• Protein Kinase R 12%
• Biochemical Assay 12%
• Minigenome 12%
• RNA-dependent RNA Polymerase (RdRP) 6%
• Virus Replication 6%
• Fatal Infection 6%
• RNA Virus 6%
• Retinoic Acid-inducible Gene I (RIG-I) 6%
• Virus-host Interactions 6%
• Infected Cells 6%
• Interferon-α (IFN-α) 6%
• Severe Disease 6%
• Response to Infection 6%
• Virus-infected Cell 6%
• Host Immune Response 6%
• Non-self 6%
• Viral Pathogenesis 6%
• Mechanistic Insight 6%
• Host Innate Immune Response 6%
• Co-infection 6%
• Differential Hosts 6%

Immunology and Microbiology

• New World Arenavirus 100%
• Lassa Virus 100%
• Nucleoprotein 85%
• Virus 64%
• Arenaviridae 42%
• Viral Disease 35%
• Interferon Type I 35%
• Machupo Virus 35%
• Innate Immune System 28%
• Host 21%
• Contrast 14%
• Cells 14%
• Human 7%
• Gene 7%
• Viral Replication 7%
• RNA Polymerase 7%
• Infectious Agent 7%
• RNA Virus 7%
• Immunosuppressive Drug 7%
• Host Immune Response 7%
• Viral Pathogenesis 7%
• Coinfection 7%

INIS

• accumulation 100%
• rna 100%
• viruses 100%
• nucleoproteins 38%
• proteins 16%
• interferon 16%
• host 12%
• sensors 9%
• signals 6%
• kinases 6%
• diseases 3%
• pathogenesis 3%
• humans 3%
• genes 3%
• levels 3%
• rna polymerases 3%
• mutations 3%
• pathogens 3%
• harbors 3%
• retinoic acid 3%