Lack of stability of the RDC endogenous subtype in consecutive episodes of major depression

Michael A. Young; Martin B. Keller; Phillip W. Lavori; William A. Scheftner; Jan A. Fawcett; Jean Endicott; Robert M.A. Hirschfeld

doi:10.1016/0165-0327(87)90006-1

Lack of stability of the RDC endogenous subtype in consecutive episodes of major depression

Michael A. Young, Martin B. Keller, Phillip W. Lavori, William A. Scheftner, Jan A. Fawcett, Jean Endicott, Robert M.A. Hirschfeld

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

The stability of the endogenous subtype of major depressive disorder was examined within individuals across consecutive episodes. The subjects were 119 probands from the NIMH Collaborative Depression Study who experienced at least two episodes of unipolar major depressive disorder within a two-year period of biannual evaluations. Structured data collection methods and Research Diagnostic Criteria were employed. The inter-episode stability of subtype diagnosis was low, never producing a kappa of greater than 0.25. This result was not attributable to threshold for diagnosis, time between episodes, differences in severity, or changes in raters.

Original language	English (US)
Pages (from-to)	139-143
Number of pages	5
Journal	Journal of Affective Disorders
Volume	12
Issue number	2
DOIs	https://doi.org/10.1016/0165-0327(87)90006-1
State	Published - 1987
Externally published	Yes

Keywords

(Stability)
Endogenous subtype
Episodes
Major depression
RDC

ASJC Scopus subject areas

Clinical Psychology
Psychiatry and Mental health

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10.1016/0165-0327(87)90006-1

Cite this

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title = "Lack of stability of the RDC endogenous subtype in consecutive episodes of major depression",

abstract = "The stability of the endogenous subtype of major depressive disorder was examined within individuals across consecutive episodes. The subjects were 119 probands from the NIMH Collaborative Depression Study who experienced at least two episodes of unipolar major depressive disorder within a two-year period of biannual evaluations. Structured data collection methods and Research Diagnostic Criteria were employed. The inter-episode stability of subtype diagnosis was low, never producing a kappa of greater than 0.25. This result was not attributable to threshold for diagnosis, time between episodes, differences in severity, or changes in raters.",

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T1 - Lack of stability of the RDC endogenous subtype in consecutive episodes of major depression

AU - Young, Michael A.

AU - Keller, Martin B.

AU - Lavori, Phillip W.

AU - Scheftner, William A.

AU - Fawcett, Jan A.

AU - Endicott, Jean

AU - Hirschfeld, Robert M.A.

PY - 1987

Y1 - 1987

N2 - The stability of the endogenous subtype of major depressive disorder was examined within individuals across consecutive episodes. The subjects were 119 probands from the NIMH Collaborative Depression Study who experienced at least two episodes of unipolar major depressive disorder within a two-year period of biannual evaluations. Structured data collection methods and Research Diagnostic Criteria were employed. The inter-episode stability of subtype diagnosis was low, never producing a kappa of greater than 0.25. This result was not attributable to threshold for diagnosis, time between episodes, differences in severity, or changes in raters.

AB - The stability of the endogenous subtype of major depressive disorder was examined within individuals across consecutive episodes. The subjects were 119 probands from the NIMH Collaborative Depression Study who experienced at least two episodes of unipolar major depressive disorder within a two-year period of biannual evaluations. Structured data collection methods and Research Diagnostic Criteria were employed. The inter-episode stability of subtype diagnosis was low, never producing a kappa of greater than 0.25. This result was not attributable to threshold for diagnosis, time between episodes, differences in severity, or changes in raters.

KW - (Stability)

KW - Endogenous subtype

KW - Episodes

KW - Major depression

KW - RDC

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Lack of stability of the RDC endogenous subtype in consecutive episodes of major depression

Abstract

Keywords

ASJC Scopus subject areas

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