Infliximab in the treatment of ulcerative colitis with toxic megacolon

Parupudi V.J. Sriram; K. S.Pavan Reddy; Guduru V. Rao; Darisetty Santosh; Duvvuru Nageshwar Reddy

Infliximab in the treatment of ulcerative colitis with toxic megacolon

Parupudi V.J. Sriram, K. S.Pavan Reddy, Guduru V. Rao, Darisetty Santosh, Duvvuru Nageshwar Reddy

Research output: Contribution to journal › Article › peer-review

Abstract

Toxic megacolon is a gastrointestinal emergency requiring prompt management to avoid fatal outcome. Although a majority of patients respond to conservative treatment, those not responding have been treated with intravenous cyclosporine or emergency surgery. Infliximab has been tried in patients with severe steroid-refractory ulcerative colitis. We report the successful use of this drug in the management of toxic megacolon in a 48-year-old woman not responding to the routine measures and who refused surgery.

Original language	English (US)
Pages (from-to)	22-23
Number of pages	2
Journal	Indian Journal of Gastroenterology
Volume	23
Issue number	1
State	Published - Jan 2004
Externally published	Yes

Keywords

Inflammatory bowel disease
Ulcerative colitis

ASJC Scopus subject areas

Gastroenterology

Cite this

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title = "Infliximab in the treatment of ulcerative colitis with toxic megacolon",

abstract = "Toxic megacolon is a gastrointestinal emergency requiring prompt management to avoid fatal outcome. Although a majority of patients respond to conservative treatment, those not responding have been treated with intravenous cyclosporine or emergency surgery. Infliximab has been tried in patients with severe steroid-refractory ulcerative colitis. We report the successful use of this drug in the management of toxic megacolon in a 48-year-old woman not responding to the routine measures and who refused surgery.",

keywords = "Inflammatory bowel disease, Ulcerative colitis",

author = "Sriram, {Parupudi V.J.} and Reddy, {K. S.Pavan} and Rao, {Guduru V.} and Darisetty Santosh and Reddy, {Duvvuru Nageshwar}",

year = "2004",

month = jan,

language = "English (US)",

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AU - Sriram, Parupudi V.J.

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AU - Rao, Guduru V.

AU - Santosh, Darisetty

AU - Reddy, Duvvuru Nageshwar

PY - 2004/1

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N2 - Toxic megacolon is a gastrointestinal emergency requiring prompt management to avoid fatal outcome. Although a majority of patients respond to conservative treatment, those not responding have been treated with intravenous cyclosporine or emergency surgery. Infliximab has been tried in patients with severe steroid-refractory ulcerative colitis. We report the successful use of this drug in the management of toxic megacolon in a 48-year-old woman not responding to the routine measures and who refused surgery.

AB - Toxic megacolon is a gastrointestinal emergency requiring prompt management to avoid fatal outcome. Although a majority of patients respond to conservative treatment, those not responding have been treated with intravenous cyclosporine or emergency surgery. Infliximab has been tried in patients with severe steroid-refractory ulcerative colitis. We report the successful use of this drug in the management of toxic megacolon in a 48-year-old woman not responding to the routine measures and who refused surgery.

KW - Inflammatory bowel disease

KW - Ulcerative colitis

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AN - SCOPUS:1842763191

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JO - Indian Journal of Gastroenterology

JF - Indian Journal of Gastroenterology

IS - 1

ER -

Infliximab in the treatment of ulcerative colitis with toxic megacolon

Abstract

Keywords

ASJC Scopus subject areas

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