TY - JOUR
T1 - Infectious causes of encephalitis and meningoencephalitis in Thailand, 2003–2005
AU - LHCb collaboration
AU - Olsen, Sonja J.
AU - Campbell, Angela P.
AU - Supawat, Krongkaew
AU - Liamsuwan, Sahas
AU - Chotpitayasunondh, Tawee
AU - Laptikulthum, Somsak
AU - Viriyavejakul, Akravudh
AU - Tantirittisak, Tasanee
AU - Tunlayadechanont, Supoch
AU - Visudtibhan, Anannit
AU - Vasiknanonte, Punnee
AU - Janjindamai, Supachai
AU - Boonluksiri, Pairoj
AU - Rajborirug, Kiatsak
AU - Watanaveeradej, Veerachai
AU - Khetsuriani, Nino
AU - Dowell, Scott F.
AU - Henchaichon, Sununta
AU - Limpakarnjanarat, Khanchit
AU - Sawanpanyalert, Pathom
AU - Pongsuwanna, Yaowapa
AU - Kijphati, Rungrueng
AU - Dejsirilert, Surang
AU - Thawatsupha, Pranee
AU - Anantapreecha, Surapee
AU - Pattamadilok, Sirima
AU - Chenchittikul, Mongkol
AU - Wootha, Wattanapong
AU - Ruangsuwan, Surapee
AU - Techatuwanan, Surawit
AU - Watchaputi, Apirom
AU - Angsuwan, Pathra
AU - Dhiravibulya, Kanlaya
AU - Lusawat, Apasri
AU - Samsen, Maiyadhaj
AU - Witoonpanich, Rawiphan
AU - Chiemchanya, Surang
AU - Veerapradist, Kamol
AU - Ngaothamatasn, Weerapatn
AU - Warachit, Boonyarat
AU - Peeraputhi, Soonthorn
AU - Yodsawat, Jareerat
AU - Pinjaroen, Sutham
AU - Sathirapanya, Pornchai
AU - Setthawatcharawanich, Suwanna
AU - Nabangchang, Charcrin
AU - Phiboonbanakit, Danabhand
AU - Bresee, Joe
AU - Lingappa, Jairam
AU - Ksiazek, Thomas
PY - 2015
Y1 - 2015
N2 - Acute encephalitis is a severe neurologic syndrome. Determining etiology from among ≈100 possible agents is difficult. To identify infectious etiologies of encephalitis in Thailand, we conducted surveillance in 7 hospitals during July 2003–August 2005 and selected patients with acute onset of brain dysfunction with fever or hypothermia and with abnormalities seen on neuroimages or electroencephalograms or with cerebrospinal fluid pleocytosis. Blood and cerebrospinal fluid were tested for >30 pathogens. Among 149 case-patients, median age was 12 (range 0–83) years, 84 (56%) were male, and 15 (10%) died. Etiology was confirmed or probable for 54 (36%) and possible or unknown for 95 (64%). Among confirmed or probable etiologies, the leading pathogens were Japanese encephalitis virus, enteroviruses, and Orientia tsutsugamushi. No samples were positive for chikungunya, Nipah, or West Nile viruses; Bartonella henselae; or malaria parasites. Although a broad range of infectious agents was identified, the etiology of most cases remains unknown.
AB - Acute encephalitis is a severe neurologic syndrome. Determining etiology from among ≈100 possible agents is difficult. To identify infectious etiologies of encephalitis in Thailand, we conducted surveillance in 7 hospitals during July 2003–August 2005 and selected patients with acute onset of brain dysfunction with fever or hypothermia and with abnormalities seen on neuroimages or electroencephalograms or with cerebrospinal fluid pleocytosis. Blood and cerebrospinal fluid were tested for >30 pathogens. Among 149 case-patients, median age was 12 (range 0–83) years, 84 (56%) were male, and 15 (10%) died. Etiology was confirmed or probable for 54 (36%) and possible or unknown for 95 (64%). Among confirmed or probable etiologies, the leading pathogens were Japanese encephalitis virus, enteroviruses, and Orientia tsutsugamushi. No samples were positive for chikungunya, Nipah, or West Nile viruses; Bartonella henselae; or malaria parasites. Although a broad range of infectious agents was identified, the etiology of most cases remains unknown.
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UR - http://www.scopus.com/inward/citedby.url?scp=84928650757&partnerID=8YFLogxK
U2 - 10.3201/eid2102.140291
DO - 10.3201/eid2102.140291
M3 - Article
C2 - 25627940
AN - SCOPUS:84928650757
SN - 1080-6040
VL - 21
SP - 280
EP - 289
JO - Emerging infectious diseases
JF - Emerging infectious diseases
IS - 2
ER -