Theodore Miclau, Andrew H. Schmidt, Joseph C. Wenke, Lawrence X. Webb, Janette M. Harro, Ranjani Prabhakara, Mark E. Shirtliff

Research output: Contribution to journalReview articlepeer-review


Musculoskeletal infection is a clinical problem with significant direct healthcare costs. The prevalence of infection after closed, elective surgery is frequently estimated to be less than 2%, but in severe injuries, posttraumatic infection rates have been reported as 10% or greater. Although clinical infections are found outside the realm of medical devices, it is clear that the enormous increase of infections associated with the use of implants presents a major challenge worldwide. This review summarizes recent advances in the understanding, diagnosis, and treatment of musculoskeletal infections.

Original languageEnglish (US)
Pages (from-to)583-586
Number of pages4
JournalJournal of orthopaedic trauma
Issue number9
StatePublished - Sep 2010
Externally publishedYes


  • bacteria
  • biofilm
  • biomaterial
  • musculoskeletal infection

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine


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