In vitro erbium:YAG laser lithotripsy

Kin Foong Chan; Gracie Vargas; Patricia J. Parker; Joel M.H. Teichman; Randolph D. Glickman; H. Stan McGuff; A. J. Welch

doi:10.1117/12.388046

In vitro erbium:YAG laser lithotripsy

Kin Foong Chan, Gracie Vargas, Patricia J. Parker, Joel M.H. Teichman, Randolph D. Glickman, H. Stan McGuff, A. J. Welch

Research output: Contribution to journal › Conference article › peer-review

5 Scopus citations

Abstract

The potential application of an Erbium:YAG (Er:YAG) laser (Q_o = 50 mJ/pulse; τ_p = 275 μs; rep. rate = 2, 10 Hz) with a sapphire delivery fiber for intracorporeal laser lithotripsy was explored. Preliminary measurements on calculus mass-loss and fragmentation efficiency were conducted and results were compared with that of Ho:YAG laser lithotripsy. Laser induced bubble and lithotripsy dynamics were investigated to assess the mechanism(s) involved in the fragmentation process. Results showed that the fragmentation efficiency (mass-loss/H_o - g.μm²/J) in Er:YAG laser lithotripsy was about 2.4 times that of Ho:YAG laser lithotripsy (used: Q_o = 500 mJ/pulse; τ_p = 250 μs; rep. rate = 10 Hz). Acoustic transients were found to have minimal effect during Er:YAG laser lithotripsy. Schlieren flash images suggested a predominantly photothermal mechanism due to direct laser energy absorption, which resulted in recrystallization and plume formation. These events indicated melting and chemical decomposition of the calculus composition. Another observation led to the possibility of a plasma-mediated photothermal mechanism. The 'Moses effect' facilitating pulsed mid-infrared laser delivery appeared more efficient for the Er:YAG laser than for the Ho:YAG laser. With the sapphire fiber, experimental results suggested the potential of an improved treatment modality by the Er:YAG laser for intracorporeal laser lithotripsy.

Original language	English (US)
Pages (from-to)	198-206
Number of pages	9
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	3914
DOIs	https://doi.org/10.1117/12.388046
State	Published - 2000
Externally published	Yes
Event	Laser-Tissue Interaction XI: Photochemical, Photothermal, and Photomechanical - San Jose, CA, USA Duration: Jan 22 2000 → Jan 27 2000

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Computer Science Applications
Applied Mathematics
Electrical and Electronic Engineering

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10.1117/12.388046

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@article{441a285941e94989952738272fbeec56,

title = "In vitro erbium:YAG laser lithotripsy",

abstract = "The potential application of an Erbium:YAG (Er:YAG) laser (Qo = 50 mJ/pulse; τp = 275 μs; rep. rate = 2, 10 Hz) with a sapphire delivery fiber for intracorporeal laser lithotripsy was explored. Preliminary measurements on calculus mass-loss and fragmentation efficiency were conducted and results were compared with that of Ho:YAG laser lithotripsy. Laser induced bubble and lithotripsy dynamics were investigated to assess the mechanism(s) involved in the fragmentation process. Results showed that the fragmentation efficiency (mass-loss/Ho - g.μm2/J) in Er:YAG laser lithotripsy was about 2.4 times that of Ho:YAG laser lithotripsy (used: Qo = 500 mJ/pulse; τp = 250 μs; rep. rate = 10 Hz). Acoustic transients were found to have minimal effect during Er:YAG laser lithotripsy. Schlieren flash images suggested a predominantly photothermal mechanism due to direct laser energy absorption, which resulted in recrystallization and plume formation. These events indicated melting and chemical decomposition of the calculus composition. Another observation led to the possibility of a plasma-mediated photothermal mechanism. The 'Moses effect' facilitating pulsed mid-infrared laser delivery appeared more efficient for the Er:YAG laser than for the Ho:YAG laser. With the sapphire fiber, experimental results suggested the potential of an improved treatment modality by the Er:YAG laser for intracorporeal laser lithotripsy.",

author = "Chan, {Kin Foong} and Gracie Vargas and Parker, {Patricia J.} and Teichman, {Joel M.H.} and Glickman, {Randolph D.} and McGuff, {H. Stan} and Welch, {A. J.}",

year = "2000",

doi = "10.1117/12.388046",

language = "English (US)",

volume = "3914",

pages = "198--206",

journal = "Proceedings of SPIE - The International Society for Optical Engineering",

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publisher = "SPIE",

note = "Laser-Tissue Interaction XI: Photochemical, Photothermal, and Photomechanical ; Conference date: 22-01-2000 Through 27-01-2000",

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TY - JOUR

T1 - In vitro erbium:YAG laser lithotripsy

AU - Chan, Kin Foong

AU - Vargas, Gracie

AU - Parker, Patricia J.

AU - Teichman, Joel M.H.

AU - Glickman, Randolph D.

AU - McGuff, H. Stan

AU - Welch, A. J.

PY - 2000

Y1 - 2000

N2 - The potential application of an Erbium:YAG (Er:YAG) laser (Qo = 50 mJ/pulse; τp = 275 μs; rep. rate = 2, 10 Hz) with a sapphire delivery fiber for intracorporeal laser lithotripsy was explored. Preliminary measurements on calculus mass-loss and fragmentation efficiency were conducted and results were compared with that of Ho:YAG laser lithotripsy. Laser induced bubble and lithotripsy dynamics were investigated to assess the mechanism(s) involved in the fragmentation process. Results showed that the fragmentation efficiency (mass-loss/Ho - g.μm2/J) in Er:YAG laser lithotripsy was about 2.4 times that of Ho:YAG laser lithotripsy (used: Qo = 500 mJ/pulse; τp = 250 μs; rep. rate = 10 Hz). Acoustic transients were found to have minimal effect during Er:YAG laser lithotripsy. Schlieren flash images suggested a predominantly photothermal mechanism due to direct laser energy absorption, which resulted in recrystallization and plume formation. These events indicated melting and chemical decomposition of the calculus composition. Another observation led to the possibility of a plasma-mediated photothermal mechanism. The 'Moses effect' facilitating pulsed mid-infrared laser delivery appeared more efficient for the Er:YAG laser than for the Ho:YAG laser. With the sapphire fiber, experimental results suggested the potential of an improved treatment modality by the Er:YAG laser for intracorporeal laser lithotripsy.

AB - The potential application of an Erbium:YAG (Er:YAG) laser (Qo = 50 mJ/pulse; τp = 275 μs; rep. rate = 2, 10 Hz) with a sapphire delivery fiber for intracorporeal laser lithotripsy was explored. Preliminary measurements on calculus mass-loss and fragmentation efficiency were conducted and results were compared with that of Ho:YAG laser lithotripsy. Laser induced bubble and lithotripsy dynamics were investigated to assess the mechanism(s) involved in the fragmentation process. Results showed that the fragmentation efficiency (mass-loss/Ho - g.μm2/J) in Er:YAG laser lithotripsy was about 2.4 times that of Ho:YAG laser lithotripsy (used: Qo = 500 mJ/pulse; τp = 250 μs; rep. rate = 10 Hz). Acoustic transients were found to have minimal effect during Er:YAG laser lithotripsy. Schlieren flash images suggested a predominantly photothermal mechanism due to direct laser energy absorption, which resulted in recrystallization and plume formation. These events indicated melting and chemical decomposition of the calculus composition. Another observation led to the possibility of a plasma-mediated photothermal mechanism. The 'Moses effect' facilitating pulsed mid-infrared laser delivery appeared more efficient for the Er:YAG laser than for the Ho:YAG laser. With the sapphire fiber, experimental results suggested the potential of an improved treatment modality by the Er:YAG laser for intracorporeal laser lithotripsy.

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VL - 3914

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EP - 206

JO - Proceedings of SPIE - The International Society for Optical Engineering

JF - Proceedings of SPIE - The International Society for Optical Engineering

T2 - Laser-Tissue Interaction XI: Photochemical, Photothermal, and Photomechanical

Y2 - 22 January 2000 through 27 January 2000

ER -

In vitro erbium:YAG laser lithotripsy

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