Improving measurement of tuberculosis care cascades to enhance people-centred care

Lena Faust, Pren Naidoo, Guillermo Caceres-Cardenas, César Ugarte-Gil, Monde Muyoyeta, Andrew D. Kerkhoff, Karikalan Nagarajan, Srinath Satyanarayana, Niaina Rakotosamimanana, Simon Grandjean Lapierre, Olusola Adedeji Adejumo, Joseph Kuye, Charity Oga-Omenka, Madhukar Pai, Ramnath Subbaraman

Research output: Contribution to journalReview articlepeer-review


Care cascades represent the proportion of people reaching milestones in care for a disease and are widely used to track progress towards global targets for HIV and other diseases. Despite recent progress in estimating care cascades for tuberculosis (TB) disease, they have not been routinely applied at national and subnational levels, representing a lost opportunity for public health impact. As researchers who have estimated TB care cascades in high-incidence countries (India, Madagascar, Nigeria, Peru, South Africa, and Zambia), we describe the utility of care cascades and identify measurement challenges, including the lack of population-based disease burden data and electronic data capture, the under-reporting of people with TB navigating fragmented and privatised health systems, the heterogeneity of TB tests, and the lack of post-treatment follow-up. We outline an agenda for rectifying these gaps and argue that improving care cascade measurement is crucial to enhancing people-centred care and achieving the End TB goals.

Original languageEnglish (US)
Pages (from-to)e547-e557
JournalThe Lancet Infectious Diseases
Issue number12
StatePublished - Dec 2023
Externally publishedYes

ASJC Scopus subject areas

  • Infectious Diseases


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