TY - JOUR
T1 - Impact of sex on ventral hernia repair outcomes
T2 - A systematic review and meta-analysis
AU - Oliveira, Eduarda Sabá C.
AU - Calvi, Izabela P.
AU - Hora, David A.B.
AU - Gomes, Cintia P.
AU - Burlá, Marina M.
AU - Mao, Rui Min Diana
AU - de Figueiredo, Sergio Mazzola Poli
AU - Lu, Richard
N1 - Publisher Copyright:
© 2023 Elsevier Inc.
PY - 2023/9
Y1 - 2023/9
N2 - Background: Given the variability in abdominal physiology and hernia presentation between sexes, better comprehension of sex-related differences in outcomes would tailor surgical approach and counseling regarding postoperative outcomes. This meta-analysis aims to appraise the effect of sex on the outcomes of ventral hernia repair. Methods: A literature search in PubMed, EMBASE and Cochrane selected studies comparing outcomes of ventral hernia repair between sexes. Postoperative outcomes were assessed by pooled and meta-analysis. Statistical analysis was performed using RevMan 5.4. Results: We screened 3128 studies, reviewed 133, and included 18 observational studies, which encompassed 220,799 patients following ventral hernia repair. Postoperative chronic pain was significantly higher in female (OR 1,9; 95% CI 1,64–2,2; p < 0,001). There were no significant differences in complications, readmission, or recurrence rates between females and males. Conclusion: Female sex is associated with a higher risk of postoperative chronic pain following ventral hernia repair.
AB - Background: Given the variability in abdominal physiology and hernia presentation between sexes, better comprehension of sex-related differences in outcomes would tailor surgical approach and counseling regarding postoperative outcomes. This meta-analysis aims to appraise the effect of sex on the outcomes of ventral hernia repair. Methods: A literature search in PubMed, EMBASE and Cochrane selected studies comparing outcomes of ventral hernia repair between sexes. Postoperative outcomes were assessed by pooled and meta-analysis. Statistical analysis was performed using RevMan 5.4. Results: We screened 3128 studies, reviewed 133, and included 18 observational studies, which encompassed 220,799 patients following ventral hernia repair. Postoperative chronic pain was significantly higher in female (OR 1,9; 95% CI 1,64–2,2; p < 0,001). There were no significant differences in complications, readmission, or recurrence rates between females and males. Conclusion: Female sex is associated with a higher risk of postoperative chronic pain following ventral hernia repair.
UR - http://www.scopus.com/inward/record.url?scp=85163882959&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85163882959&partnerID=8YFLogxK
U2 - 10.1016/j.amjsurg.2023.06.026
DO - 10.1016/j.amjsurg.2023.06.026
M3 - Article
C2 - 37394348
AN - SCOPUS:85163882959
SN - 0002-9610
VL - 226
SP - 385
EP - 392
JO - American Journal of Surgery
JF - American Journal of Surgery
IS - 3
ER -