Immuno- and gene-therapeutic strategies targeted against cancer (mainly focusing on pancreatic cancer)

Kiyoshi Yoshimura; Kelly Olino; Barish H. Edil; Richard D. Schulick; Masaaki Oka

doi:10.1007/s00595-009-4120-8

Immuno- and gene-therapeutic strategies targeted against cancer (mainly focusing on pancreatic cancer)

Kiyoshi Yoshimura, Kelly Olino, Barish H. Edil, Richard D. Schulick, Masaaki Oka

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Abstract

Current treatment modalities of surgical resection and chemotherapy against cancers have improved survival. However, mortality from tumor recurrence remains high. Immunotherapy and gene therapy are potential additions to the treatment arsenal in the care of cancer patients. These novel therapeutic approaches need further investigation in in vitro and in vivo models as they are developed for potential use in humans. Here we reviewed immunotherapies and gene therapies that included clinical trials against cancers (mainly focusing on pancreatic cancer) suggesting the strong possibility of using these novel approaches.

Original language	English (US)
Pages (from-to)	404-410
Number of pages	7
Journal	Surgery Today
Volume	40
Issue number	5
DOIs	https://doi.org/10.1007/s00595-009-4120-8
State	Published - May 2010
Externally published	Yes

Keywords

Gastrointestinal cancer
Immunotherapy

ASJC Scopus subject areas

Surgery

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10.1007/s00595-009-4120-8

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title = "Immuno- and gene-therapeutic strategies targeted against cancer (mainly focusing on pancreatic cancer)",

abstract = "Current treatment modalities of surgical resection and chemotherapy against cancers have improved survival. However, mortality from tumor recurrence remains high. Immunotherapy and gene therapy are potential additions to the treatment arsenal in the care of cancer patients. These novel therapeutic approaches need further investigation in in vitro and in vivo models as they are developed for potential use in humans. Here we reviewed immunotherapies and gene therapies that included clinical trials against cancers (mainly focusing on pancreatic cancer) suggesting the strong possibility of using these novel approaches.",

keywords = "Gastrointestinal cancer, Immunotherapy",

author = "Kiyoshi Yoshimura and Kelly Olino and Edil, {Barish H.} and Schulick, {Richard D.} and Masaaki Oka",

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language = "English (US)",

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T1 - Immuno- and gene-therapeutic strategies targeted against cancer (mainly focusing on pancreatic cancer)

AU - Yoshimura, Kiyoshi

AU - Olino, Kelly

AU - Edil, Barish H.

AU - Schulick, Richard D.

AU - Oka, Masaaki

PY - 2010/5

Y1 - 2010/5

N2 - Current treatment modalities of surgical resection and chemotherapy against cancers have improved survival. However, mortality from tumor recurrence remains high. Immunotherapy and gene therapy are potential additions to the treatment arsenal in the care of cancer patients. These novel therapeutic approaches need further investigation in in vitro and in vivo models as they are developed for potential use in humans. Here we reviewed immunotherapies and gene therapies that included clinical trials against cancers (mainly focusing on pancreatic cancer) suggesting the strong possibility of using these novel approaches.

AB - Current treatment modalities of surgical resection and chemotherapy against cancers have improved survival. However, mortality from tumor recurrence remains high. Immunotherapy and gene therapy are potential additions to the treatment arsenal in the care of cancer patients. These novel therapeutic approaches need further investigation in in vitro and in vivo models as they are developed for potential use in humans. Here we reviewed immunotherapies and gene therapies that included clinical trials against cancers (mainly focusing on pancreatic cancer) suggesting the strong possibility of using these novel approaches.

KW - Gastrointestinal cancer

KW - Immunotherapy

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U2 - 10.1007/s00595-009-4120-8

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SN - 0941-1291

VL - 40

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EP - 410

JO - Surgery Today

JF - Surgery Today

IS - 5

ER -

Immuno- and gene-therapeutic strategies targeted against cancer (mainly focusing on pancreatic cancer)

Abstract

Keywords

ASJC Scopus subject areas

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