Identification of Ehrlichia in Human Tissue

J. Stephen Dumler, Philippe Brouqui, Judith Aronson, Jeffery P. Taylor, David H. Walker

Research output: Contribution to journalLetterpeer-review

53 Scopus citations


To the Editor: In 1987, Maeda et al. reported a case of human ehrlichiosis diagnosed by the serologic response to Ehrlichia canis and ultrastructural identification of clusters of small bacteria in cytoplasmic vacuoles of peripheral-blood leukocytes.1 Since that time more than 160 cases have been reported.2,3 Although the clinical and epidemiologic description of human ehrlichiosis is increasingly well defined, there have been neither published reports of isolation of the agent from humans nor proof of the antigenic identity of the ehrlichia-like organisms in clinical specimens from humans. We recently used immunohistology to identify an organism antigenically related to E. canis.

Original languageEnglish (US)
Pages (from-to)1109-1110
Number of pages2
JournalNew England Journal of Medicine
Issue number15
StatePublished - Oct 10 1991

ASJC Scopus subject areas

  • General Medicine


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