Hypolipidemic activity of eryngium carlinae on streptozotocin-induced diabetic rats

Ruth Noriega-Cisneros; Omar Ortiz-Vila; Edgar Esquivel-Gutiérrez; Mnica Clemente-Guerrero; Salvador Manzo-Avalos; Rafael Salgado-Garciglia; Christian Cortés-Rojo; Istvan Boldogh; Alfredo Saavedra-Molina

doi:10.1155/2012/603501

Hypolipidemic activity of eryngium carlinae on streptozotocin-induced diabetic rats

Ruth Noriega-Cisneros, Omar Ortiz-Vila, Edgar Esquivel-Gutiérrez, Mnica Clemente-Guerrero, Salvador Manzo-Avalos, Rafael Salgado-Garciglia, Christian Cortés-Rojo, Istvan Boldogh, Alfredo Saavedra-Molina

Microbiology And Immunology

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Diabetes mellitus (DM) is a significant risk factor for the development of cardiovascular complications. This study was undertaken to investigate the effect of chronic administration of ethanolic extract of Eryngium carlinae on glucose, creatinine, uric acid, total cholesterol, and triglycerides levels in serum of streptozotocin- (STZ-) induced diabetic rats. Triglycerides, total cholesterol, and uric acid levels increased in serum from diabetic rats. The treatment with E. carlinae prevented these changes. The administration of E. carlinae extract reduced the levels of creatinine, uric acid, total cholesterol, and triglycerides. Thus administration of E. carlinae is able to reduce hyperlipidemia related to the cardiovascular risk in diabetes mellitus.

Original language	English (US)
Article number	603501
Journal	Biochemistry Research International
DOIs	https://doi.org/10.1155/2012/603501
State	Published - 2012

ASJC Scopus subject areas

Biochemistry

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abstract = "Diabetes mellitus (DM) is a significant risk factor for the development of cardiovascular complications. This study was undertaken to investigate the effect of chronic administration of ethanolic extract of Eryngium carlinae on glucose, creatinine, uric acid, total cholesterol, and triglycerides levels in serum of streptozotocin- (STZ-) induced diabetic rats. Triglycerides, total cholesterol, and uric acid levels increased in serum from diabetic rats. The treatment with E. carlinae prevented these changes. The administration of E. carlinae extract reduced the levels of creatinine, uric acid, total cholesterol, and triglycerides. Thus administration of E. carlinae is able to reduce hyperlipidemia related to the cardiovascular risk in diabetes mellitus.",

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AU - Noriega-Cisneros, Ruth

AU - Ortiz-Vila, Omar

AU - Esquivel-Gutiérrez, Edgar

AU - Clemente-Guerrero, Mnica

AU - Manzo-Avalos, Salvador

AU - Salgado-Garciglia, Rafael

AU - Cortés-Rojo, Christian

AU - Boldogh, Istvan

AU - Saavedra-Molina, Alfredo

PY - 2012

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N2 - Diabetes mellitus (DM) is a significant risk factor for the development of cardiovascular complications. This study was undertaken to investigate the effect of chronic administration of ethanolic extract of Eryngium carlinae on glucose, creatinine, uric acid, total cholesterol, and triglycerides levels in serum of streptozotocin- (STZ-) induced diabetic rats. Triglycerides, total cholesterol, and uric acid levels increased in serum from diabetic rats. The treatment with E. carlinae prevented these changes. The administration of E. carlinae extract reduced the levels of creatinine, uric acid, total cholesterol, and triglycerides. Thus administration of E. carlinae is able to reduce hyperlipidemia related to the cardiovascular risk in diabetes mellitus.

AB - Diabetes mellitus (DM) is a significant risk factor for the development of cardiovascular complications. This study was undertaken to investigate the effect of chronic administration of ethanolic extract of Eryngium carlinae on glucose, creatinine, uric acid, total cholesterol, and triglycerides levels in serum of streptozotocin- (STZ-) induced diabetic rats. Triglycerides, total cholesterol, and uric acid levels increased in serum from diabetic rats. The treatment with E. carlinae prevented these changes. The administration of E. carlinae extract reduced the levels of creatinine, uric acid, total cholesterol, and triglycerides. Thus administration of E. carlinae is able to reduce hyperlipidemia related to the cardiovascular risk in diabetes mellitus.

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Hypolipidemic activity of eryngium carlinae on streptozotocin-induced diabetic rats

Abstract

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