Hydrogen sulfide: A metabolic modulator and a protective agent in animal models of reperfusion injury

C. Szabó, P. Asfar, P. Radermacher

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Hydrogen sulfide (H2S), a gas with the characteristic odor of rotten eggs, is known for its toxicity and as an environmental hazard [1-5]. Recently H2S has been recognized as a signaling molecule of the cardiovascular, inflammatory and nervous systems. Alongside with nitric oxide (NO) and carbon monoxide, it is now referred to as the third endogenous gaseous transmitter [6]. Inhalation of gaseous H2S and administration of compounds that donate H2S have been studied in various models of ischemia-reperfusion and circulatory shock [7-24].

Original languageEnglish (US)
Title of host publicationYearbook of Intensive Care and Emergency Medicine 2009
PublisherSpringer New York
Pages171-179
Number of pages9
ISBN (Print)9780387922775
DOIs
StatePublished - 2007
Externally publishedYes

ASJC Scopus subject areas

  • General Medicine

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