How, When, and Why: High-Density Mapping of Atrial Fibrillation

Santhisri Kodali, Pasquale Santangeli

Research output: Contribution to journalReview articlepeer-review


High-density (HD) mapping presents opportunities to enhance delineation of atrial fibrillation (AF) substrate, improve efficiency of the mapping procedure without sacrificing safety, and afford new mechanistic insights regarding AF. Innovations in hardware, software algorithms, and development of novel multielectrode catheters have allowed HD mapping to be feasible and reliable. Patients to particularly benefit from this technology are those with paroxysmal AF in setting of preexisting atrial scar, persistent AF, and AF in the setting of complex congenital heart disease. The future will bring refinements in automated HD mapping including evolution of noncontact methodologies and artificial intelligence to supplant current techniques.

Original languageEnglish (US)
Pages (from-to)155-165
Number of pages11
JournalCardiac Electrophysiology Clinics
Issue number2
StatePublished - Jun 2020
Externally publishedYes


  • Atrial fibrillation
  • Catheter ablation
  • High-density mapping

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)


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