Hippocampal Lesions Following Administration of 3-Acetylpyridine

Richard E. Coggeshall, Paul D. MacLean

Research output: Contribution to journalArticlepeer-review

35 Scopus citations


Administration of 3-acetylpy-ridine (3AP) to non-inbred, adult mice results in cerebral changes restricted almost exclusively to areas CA3 and CA4 of the hippocampus. Ability to induce such lesions in chronic preparations has encouraged extension of this investigation to cats and monkeys with the eventual purpose of performing behavioral studies concerned with elucidating the functions of the hippocampus.

Original languageEnglish (US)
Pages (from-to)687-689
Number of pages3
JournalProceedings of the Society for Experimental Biology and Medicine
Issue number4
StatePublished - 1958
Externally publishedYes

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology


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