Hibernoma: A report of 2 unusual cases with a review of the literature

Subodh M. Lele, Satish Chundru, Gregory Chaljub, Patrick Adegboyega, Abida K. Haque

Research output: Contribution to journalArticlepeer-review

36 Scopus citations


Hibernomas are rare neoplasms composed of brown adipose tissue. The behavior of these neoplasms has been described as uniformly benign in humans. The only recurrence cited in the English literature involved a sarcoma with hibernoma-like features, which was reported in abstract form. We present 2 cases of hibernoma, one that continued to grow following partial excision and another at an unusual site (anterior abdominal wall). Both of these tumors overexpressed p53 protein by immunohistochemistry, which was a novel finding. A review of the literature highlights recent advances that may help confirm the diagnosis and explain the biology of these rare tumors.

Original languageEnglish (US)
Pages (from-to)975-978
Number of pages4
JournalArchives of Pathology and Laboratory Medicine
Issue number8
StatePublished - Aug 2002
Externally publishedYes

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology


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