Graft-versus-host disease: Gastrointestinal involvement with a rectovaginal fistula

Bradley H. Kessler; William J. Cochran; Milton L. Wagner; Hal K. Hawkins; William J. Klish

doi:10.1097/00005176-198803000-00022

Graft-versus-host disease: Gastrointestinal involvement with a rectovaginal fistula

Bradley H. Kessler, William J. Cochran, Milton L. Wagner, Hal K. Hawkins, William J. Klish

Research output: Contribution to journal › Article › peer-review

Abstract

Bone marrow transplantation is an accepted form of treatment for aplastic anemia and end-stage hematological malignancies. Despite a satisfactory outcome in selected patients, more than one-half develop acute graft-versus-host disease (GVHD), characterized typically by involvement of the skin, liver, and gastrointestinal tract. We describe an unusual case in which a 10year-old girl developed gastrointestinal symptoms as the only manifestation of GVHD. The patient presented with a rectovaginal fistula and had clinical, radiological, and histological features of gastrointestinal GVHD without evidence of liver or skin involvement.

Original language	English (US)
Pages (from-to)	288-292
Number of pages	5
Journal	Journal of Pediatric Gastroenterology and Nutrition
Volume	7
Issue number	2
DOIs	https://doi.org/10.1097/00005176-198803000-00022
State	Published - Mar 1988
Externally published	Yes

Keywords

Aplastic anemia
Gastrointestinal graft-versus-host disease
Gastrointestinal involvement
Graft-versus-host disease

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Gastroenterology

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10.1097/00005176-198803000-00022

Cite this

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title = "Graft-versus-host disease: Gastrointestinal involvement with a rectovaginal fistula",

abstract = "Bone marrow transplantation is an accepted form of treatment for aplastic anemia and end-stage hematological malignancies. Despite a satisfactory outcome in selected patients, more than one-half develop acute graft-versus-host disease (GVHD), characterized typically by involvement of the skin, liver, and gastrointestinal tract. We describe an unusual case in which a 10year-old girl developed gastrointestinal symptoms as the only manifestation of GVHD. The patient presented with a rectovaginal fistula and had clinical, radiological, and histological features of gastrointestinal GVHD without evidence of liver or skin involvement.",

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T2 - Gastrointestinal involvement with a rectovaginal fistula

AU - Kessler, Bradley H.

AU - Cochran, William J.

AU - Wagner, Milton L.

AU - Hawkins, Hal K.

AU - Klish, William J.

PY - 1988/3

Y1 - 1988/3

N2 - Bone marrow transplantation is an accepted form of treatment for aplastic anemia and end-stage hematological malignancies. Despite a satisfactory outcome in selected patients, more than one-half develop acute graft-versus-host disease (GVHD), characterized typically by involvement of the skin, liver, and gastrointestinal tract. We describe an unusual case in which a 10year-old girl developed gastrointestinal symptoms as the only manifestation of GVHD. The patient presented with a rectovaginal fistula and had clinical, radiological, and histological features of gastrointestinal GVHD without evidence of liver or skin involvement.

AB - Bone marrow transplantation is an accepted form of treatment for aplastic anemia and end-stage hematological malignancies. Despite a satisfactory outcome in selected patients, more than one-half develop acute graft-versus-host disease (GVHD), characterized typically by involvement of the skin, liver, and gastrointestinal tract. We describe an unusual case in which a 10year-old girl developed gastrointestinal symptoms as the only manifestation of GVHD. The patient presented with a rectovaginal fistula and had clinical, radiological, and histological features of gastrointestinal GVHD without evidence of liver or skin involvement.

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KW - Gastrointestinal graft-versus-host disease

KW - Gastrointestinal involvement

KW - Graft-versus-host disease

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Graft-versus-host disease: Gastrointestinal involvement with a rectovaginal fistula

Abstract

Keywords

ASJC Scopus subject areas

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