Gradenigo's syndrome in a four-year-old patient: A rare diagnosis in the modern antibiotic era

N. Rossi, M. L. Swonke, L. Reichert, D. Young

Research output: Contribution to journalArticlepeer-review


Objective This study gives details of a rare case of petrous apicitis that presented as Gradenigo's syndrome and was managed surgically.Method This study presents a case report and review of the literature.Results A four-year-old female was admitted for failure to thrive following recent sinusitis. Physical examination was positive for right sided facial pain, photophobia and right abducens nerve palsy. Subsequent magnetic resonance imaging revealed a 1.3 × 1.7 × 1.4 cm abscess encompassing the right Meckel's cave. A computed tomography scan showed petrous apicitis and otomastoiditis, confirming Gradenigo's syndrome. The patient was taken to the operating theatre for right intact canal wall mastoidectomy with myringotomy and tube placement. She was discharged on six weeks of ceftriaxone administered by a peripherally inserted central catheter line. At a two-week post-operative visit, she showed notable improvement in neuropathic symptoms.Conclusion This study presents a rare case of petrous apicitis managed surgically without the need for a craniotomy or transcochlear procedure.

Original languageEnglish (US)
Pages (from-to)535-537
Number of pages3
JournalJournal of Laryngology and Otology
Issue number6
StatePublished - Jun 1 2019
Externally publishedYes


  • Abducens Nerve
  • Abducens Nerve Diseases
  • Mastoidectomy
  • Mastoiditis
  • Petrositis
  • Temporal Bone
  • Trigeminal Nerve
  • Vestibulocochlear Nerve

ASJC Scopus subject areas

  • Otorhinolaryngology


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