Giant ameloblastoma: Report of an extreme case and a description of its treatment

C. Anthony Hughes, William R. Wilson, Michael Olding

Research output: Contribution to journalArticlepeer-review


Ameloblastoma is an odontogenic tumor that usually occurs in the mandible. It is an aggressive but benign tumor of epithelial origin that is rarely metastatic. We report the case of a 53-year-old woman who had a massive ameloblastoma of the mandible. The tumor measured 15.2 x 11.4 x 12.0 cm. The patient had oral bleeding that required a transfusion. The workup included three-dimensional imaging, arteriography, and embolization to control bleeding. Surgical management entailed the resection of the entire left mandible and right symphysis, followed by reconstruction with a free fibular flap. To our knowledge, this is the largest reported ameloblastoma managed with three-dimensional imaging, radical resection, and free-flap reconstruction. This article also reviews aspects of the differential diagnosis, pathology, and management of jaw tumors.

Original languageEnglish (US)
Pages (from-to)568-579
Number of pages12
JournalEar, Nose and Throat Journal
Issue number8
StatePublished - 1999
Externally publishedYes

ASJC Scopus subject areas

  • Otorhinolaryngology


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