TY - JOUR
T1 - Genomic and phylogenetic characterization of Leanyer virus, a novel orthobunyavirus isolated in northern Australia
AU - Savji, Nazir
AU - Palacios, Gustavo
AU - da Rosa, Amelia Travassos
AU - Hutchison, Stephen
AU - Celone, Christopher
AU - Hui, Jeffrey
AU - Briese, Thomas
AU - Calisher, Charles H.
AU - Tesh, Robert B.
AU - Lipkin, W. Ian
PY - 2011/7
Y1 - 2011/7
N2 - Leanyer virus (LEAV), currently classified as a member of the genus Orthobunyavirus, in the family Bunyaviridae, was originally isolated from a pool of Anopheles meraukensis mosquitoes, collected at Leanyer, Northern Territory, Australia in 1974. When it failed to react in serological tests with antisera from other known viruses, full-length genomic sequencing was pursued to determine the relationship of LEAV to other orthobunyavirus species. Genetic and serological characterization confirmed its antigenic distance from other orthobunyaviruses, including to its closest genetic neighbours, the Simbu group viruses, suggesting that it may represent a new antigenic complex.
AB - Leanyer virus (LEAV), currently classified as a member of the genus Orthobunyavirus, in the family Bunyaviridae, was originally isolated from a pool of Anopheles meraukensis mosquitoes, collected at Leanyer, Northern Territory, Australia in 1974. When it failed to react in serological tests with antisera from other known viruses, full-length genomic sequencing was pursued to determine the relationship of LEAV to other orthobunyavirus species. Genetic and serological characterization confirmed its antigenic distance from other orthobunyaviruses, including to its closest genetic neighbours, the Simbu group viruses, suggesting that it may represent a new antigenic complex.
UR - http://www.scopus.com/inward/record.url?scp=79959298628&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79959298628&partnerID=8YFLogxK
U2 - 10.1099/vir.0.028308-0
DO - 10.1099/vir.0.028308-0
M3 - Article
C2 - 21402599
AN - SCOPUS:79959298628
SN - 0022-1317
VL - 92
SP - 1676
EP - 1687
JO - Journal of General Virology
JF - Journal of General Virology
IS - 7
ER -