Generation of antigen-specific, Foxp3-expressing CD4⁺ regulatory T cells by inhibition of APC proteosome function

Keyphrases

• Regulatory T (Treg) Cells 100%
• Antigen-specific 100%
• Proteosome 100%
• Forkhead Box P3 (FOXP3) 100%
• CD4+ Regulatory T Cells 100%
• T Cells 40%
• Interleukin-10 40%
• NF-B 40%
• Interleukin-2 40%
• Signaling Pathway 20%
• Inhibitory Effect 20%
• CD4+ T Cells 20%
• Treg 20%
• Th1 Response 20%
• Protease Inhibitors 20%
• Memory CD4+ T Cells 20%
• Colitis 20%
• Cytotoxic T-lymphocyte-associated Protein 4 (CTLA-4) 20%
• Tert-butyl 20%
• IL-10 Production 20%
• Cell Inhibition 20%
• CD25+ 20%
• Secondary Culture 20%
• Cell-cell Contact 20%

INIS

• antigens 100%
• in vivo 100%
• inhibition 100%
• hypothesis 50%
• production 50%
• in vitro 50%
• levels 50%
• proliferation 50%
• maturation 50%

Immunology and Microbiology

• Antigen Specificity 100%
• CD4 100%
• Regulatory T Cell 100%
• Antigen-Presenting Cell 100%
• Cells 60%
• T Cell 20%
• Memory 20%
• T-Helper Cell 20%
• Differentiation 10%
• Signal Transduction 10%
• Maturation 10%
• Colitis 10%
• CTLA-4 10%
• CD25 10%
• Cell Contact 10%