Gastrointestinal System, Obesity, and Body Composition

Ann O. Scheimann, Roman Shypailo, Phillip D.K. Lee

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Obesity or increased body fat is arguably the most characteristic physical feature of Prader-Willi syndrome (PWS). Perhaps for this reason, a vast majority of the publications regarding PWS mention, discuss, and/or explore the topic of obesity. Despite this attention, the diagnosis, pathogenesis, optimal treatment, monitoring, and outcome of this condition in PWS remain controversial and incompletely defined. The paradox of the underweight infant with PWS evolving into an overweight child and adult has led to considerable speculation regarding pathophysiology. In addition, there is an inappropriate interchangeable use of the terms obesity, body mass index (BMI), and weight in the medical and scientific literature.

Original languageEnglish (US)
Title of host publicationManagement of Prader-Willi Syndrome
Subtitle of host publicationFourth Edition
PublisherSpringer International Publishing
Pages159-194
Number of pages36
ISBN (Electronic)9783030981716
ISBN (Print)9783030981709
DOIs
StatePublished - Jan 1 2022
Externally publishedYes

ASJC Scopus subject areas

  • General Medicine

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