Gastrointestinal Behçet's disease: Manifestations, diagnosis, and management

Zara Manuelyan, Edward Butt, Sreeram Parupudi

Research output: Contribution to journalArticlepeer-review


Behçet's disease (BD) is a rare, inflammatory vascular disorder with recurrent oral and genital aphthous ulcers, along with ocular and cutaneous manifestations. Gastrointestinal (GI) BD may involve any portion of the GI tract. However, it is commonly described in the terminal ileum, followed by the ileocecal region. Diagnosis is challenging given lack of pathognomonic tests; therefore, it is based on clinical criteria. Management of intestinal BD includes different classes of medications including corticosteroids, 5-aminosalicylic acid, immunomodulators, and anti-tumor necrosis factor alpha monoclonal antibody agents. In this review, we aim to focus on intestinal BD and provide details of clinical manifestations, diagnosis and therapeutic options of intestinal BD from gastroenterology viewpoint.

Original languageEnglish (US)
Article number101674
Issue number1
StatePublished - Jan 2024
Externally publishedYes


  • Behçet's disease
  • Intestinal Behçet's
  • Therapeutic regimen
  • disease activity index for intestinal Behçet's disease

ASJC Scopus subject areas

  • General Medicine


Dive into the research topics of 'Gastrointestinal Behçet's disease: Manifestations, diagnosis, and management'. Together they form a unique fingerprint.

Cite this