Fractional flow reserve measurement by computed tomography: An alternative to the stress test

Ji Hyun Lee, Bríain Hartaigh, Donghee Han, Asim Rizvi, Fay Y. Lin, James K. Min

Research output: Contribution to journalArticlepeer-review


Recent advances in computed tomographic technology have contributed towards improving coronary computed tomography angiography (CCTA) in determining the severity of coronary artery disease anatomically. Although the viability of CCTA has most often been confined to anatomical assessment, recent development has enabled evaluation of the haemodynamic significance of coronary artery disease. In light of this, CCTA-derived fractional flow reserve (FFRCT), a novel imaging modality, now permits the physiological assessment of coronary artery disease. To date, several studies have documented the diagnostic performance of FFRCT, and more trials are being performed that will further substantiate this technique. The present paper provides an overview and discussion of the available evidence for FFRCT in the clinical setting as well as potential future directions of FFRCT.

Original languageEnglish (US)
Pages (from-to)105-109
Number of pages5
JournalInterventional Cardiology: Reviews, Research, Resources
Issue number2
StatePublished - 2016
Externally publishedYes


  • Coronary artery disease
  • Coronary computed tomography angiography
  • Fractional flow reserve
  • Stress imaging test

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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