Flumazenil for the reversal of refractory benzodiazepine-induced shock

Wendy Coates, Timothy C. Evans, Dietrich Jehle, Fred Harchelroad, Marshal Isaacs

Research output: Contribution to journalArticlepeer-review


Benzodiazepines are known to cause central nervous system and centrally mediated cardiovascular depression. The benzodiazepine antagonist flumazenil has been shown to antagonize benzodiazepine-induced central nervous system depression. We report a case in which cardiovascular depression secondary to benzodiazepine use was reversed by this agent.

Original languageEnglish (US)
Pages (from-to)537-542
Number of pages6
JournalClinical Toxicology
Issue number4
StatePublished - 1991
Externally publishedYes


  • Benzodiazepine-induced shock
  • Flumazenil

ASJC Scopus subject areas

  • Toxicology


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