TY - JOUR
T1 - First molecular characterization and phylogenetic analysis of the VP2 gene of feline panleukopenia virus in Bangladesh
AU - Chowdhury, Q. M.Monzur Kader
AU - Alam, Shahrul
AU - Chowdhury, Md Shahidur Rahman
AU - Hasan, Mahmudul
AU - Uddin, Md Bashir
AU - Hossain, Md Mukter
AU - Islam, Md Rafiqul
AU - Rahman, Md Masudur
AU - Rahman, Md Mahfujur
N1 - Publisher Copyright:
© 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature.
PY - 2021/8
Y1 - 2021/8
N2 - Feline panleukopenia virus (FPV) is a highly contagious infectious pathogen of cats globally. However, there is no information on the molecular identification and characterization of FPV in Bangladesh. Here, 8.16% (8/98) and 18.37% (18/98) of diarrheic cats tested positive for FPV by an immunochromatography (IC) test and PCR, respectively. The IC test showed 44.44% sensitivity and 100% specificity in comparison with PCR. Our newly sequenced Bangladeshi FPV strain (MN826076) showed the highest (99.71%) sequence identity to strains from the United Arab Emirates (UAE). Strain MN826076 contained two characteristic amino acid variations in VP2 identifying it as an FPV strain: valine at position 103 and aspartic acid at position 323. Phylogenetically, the VP2 of strain MN826076 was found to be closely related to 19 FPV strains, sharing the same clade.
AB - Feline panleukopenia virus (FPV) is a highly contagious infectious pathogen of cats globally. However, there is no information on the molecular identification and characterization of FPV in Bangladesh. Here, 8.16% (8/98) and 18.37% (18/98) of diarrheic cats tested positive for FPV by an immunochromatography (IC) test and PCR, respectively. The IC test showed 44.44% sensitivity and 100% specificity in comparison with PCR. Our newly sequenced Bangladeshi FPV strain (MN826076) showed the highest (99.71%) sequence identity to strains from the United Arab Emirates (UAE). Strain MN826076 contained two characteristic amino acid variations in VP2 identifying it as an FPV strain: valine at position 103 and aspartic acid at position 323. Phylogenetically, the VP2 of strain MN826076 was found to be closely related to 19 FPV strains, sharing the same clade.
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U2 - 10.1007/s00705-021-05113-y
DO - 10.1007/s00705-021-05113-y
M3 - Article
C2 - 34059971
AN - SCOPUS:85107284543
SN - 0304-8608
VL - 166
SP - 2273
EP - 2278
JO - Archives of virology
JF - Archives of virology
IS - 8
ER -