TY - JOUR
T1 - EVOLUTION OF NEW GENOTYPE OF WEST NILE VIRUS IN NORTH AMERICA
AU - McMullen, Allison R.
AU - May, Fiona J.
AU - Li, Li
AU - Guzman, Hilda
AU - Bueno, Rudy
AU - Dennett, James A.
AU - Tesh, Robert B.
AU - Barrett, Alan D.T.
N1 - Publisher Copyright:
© 2011, Amaltea Medical Publishing House. All rights reserved.
PY - 2011
Y1 - 2011
N2 - Previous studies of North American isolates of West Nile virus (WNV, during 1999-2005) suggested that the virus had reached genetic homeostasis in North America. However, genomic sequencing of WNV isolates from Harris County, Texas, during 2002-2009 suggests that this is not the case. Three new genetic groups have been identifi ed in Texas since 2005. Spread of the southwestern US genotype (SW/WN03) from the Arizona/Colorado/northern Mexico region to California, Illinois, New Mexico, New York, North Dakota, and the Texas Gulf Coast demonstrates continued evolution of WNV. Thus, WNV continues to evolve in North America as demonstrated by selection of this new genotype. Continued surveillance of the virus is essential as it continues to evolve in the New World.
AB - Previous studies of North American isolates of West Nile virus (WNV, during 1999-2005) suggested that the virus had reached genetic homeostasis in North America. However, genomic sequencing of WNV isolates from Harris County, Texas, during 2002-2009 suggests that this is not the case. Three new genetic groups have been identifi ed in Texas since 2005. Spread of the southwestern US genotype (SW/WN03) from the Arizona/Colorado/northern Mexico region to California, Illinois, New Mexico, New York, North Dakota, and the Texas Gulf Coast demonstrates continued evolution of WNV. Thus, WNV continues to evolve in North America as demonstrated by selection of this new genotype. Continued surveillance of the virus is essential as it continues to evolve in the New World.
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M3 - Article
AN - SCOPUS:85142833021
SN - 1454-3389
VL - 14
SP - 57
EP - 65
JO - Romanian Journal of Infectious Diseases
JF - Romanian Journal of Infectious Diseases
IS - 2
ER -