Evolution of 2014/15 H3N2 influenza viruses circulating in US: Consequences for vaccine effectiveness and possible new pandemic

Veljko Veljkovic; Slobodan Paessler; Sanja Glisic; Jelena Prljic; Vladimir R. Perovic; Nevena Veljkovic; Matthew Scotch

doi:10.3389/fmicb.2015.01456

Evolution of 2014/15 H3N2 influenza viruses circulating in US: Consequences for vaccine effectiveness and possible new pandemic

Veljko Veljkovic, Slobodan Paessler, Sanja Glisic, Jelena Prljic, Vladimir R. Perovic, Nevena Veljkovic, Matthew Scotch

Pathology

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

A key factor in the effectiveness of the seasonal influenza vaccine is its immunological compatibility with the circulating viruses during the season. Here we propose a new bioinformatics approach for analysis of influenza viruses which could be used as an efficient tool for selection of vaccine viruses, assessment of the effectiveness of seasonal influenza vaccines, and prediction of the epidemic/pandemic potential of novel influenza viruses.

Original language	English (US)
Article number	01456
Journal	Frontiers in Microbiology
Volume	6
Issue number	DEC
DOIs	https://doi.org/10.3389/fmicb.2015.01456
State	Published - 2015

Keywords

H3N2
Influenza virus
Pandemic potential
Phylogenetic analysis
Seasonal influenza vaccine effectiveness

ASJC Scopus subject areas

Microbiology
Microbiology (medical)

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10.3389/fmicb.2015.01456

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title = "Evolution of 2014/15 H3N2 influenza viruses circulating in US: Consequences for vaccine effectiveness and possible new pandemic",

abstract = "A key factor in the effectiveness of the seasonal influenza vaccine is its immunological compatibility with the circulating viruses during the season. Here we propose a new bioinformatics approach for analysis of influenza viruses which could be used as an efficient tool for selection of vaccine viruses, assessment of the effectiveness of seasonal influenza vaccines, and prediction of the epidemic/pandemic potential of novel influenza viruses.",

keywords = "H3N2, Influenza virus, Pandemic potential, Phylogenetic analysis, Seasonal influenza vaccine effectiveness",

author = "Veljko Veljkovic and Slobodan Paessler and Sanja Glisic and Jelena Prljic and Perovic, {Vladimir R.} and Nevena Veljkovic and Matthew Scotch",

note = "Publisher Copyright: {\textcopyright} 2015 Veljkovic, Paessler, Glisic, Prljic, Perovic, Veljkovic and Scotch.",

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journal = "Frontiers in Microbiology",

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T2 - Consequences for vaccine effectiveness and possible new pandemic

AU - Veljkovic, Veljko

AU - Paessler, Slobodan

AU - Glisic, Sanja

AU - Prljic, Jelena

AU - Perovic, Vladimir R.

AU - Veljkovic, Nevena

AU - Scotch, Matthew

PY - 2015

Y1 - 2015

N2 - A key factor in the effectiveness of the seasonal influenza vaccine is its immunological compatibility with the circulating viruses during the season. Here we propose a new bioinformatics approach for analysis of influenza viruses which could be used as an efficient tool for selection of vaccine viruses, assessment of the effectiveness of seasonal influenza vaccines, and prediction of the epidemic/pandemic potential of novel influenza viruses.

AB - A key factor in the effectiveness of the seasonal influenza vaccine is its immunological compatibility with the circulating viruses during the season. Here we propose a new bioinformatics approach for analysis of influenza viruses which could be used as an efficient tool for selection of vaccine viruses, assessment of the effectiveness of seasonal influenza vaccines, and prediction of the epidemic/pandemic potential of novel influenza viruses.

KW - H3N2

KW - Influenza virus

KW - Pandemic potential

KW - Phylogenetic analysis

KW - Seasonal influenza vaccine effectiveness

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ER -

Evolution of 2014/15 H3N2 influenza viruses circulating in US: Consequences for vaccine effectiveness and possible new pandemic

Abstract

Keywords

ASJC Scopus subject areas

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