Evaluation of biodegradable adjunctive therapy for extremity wound infection reduction

J. Jennings; S. Noel; B. Reves; K. Smith; S. Jackson; J. Bumgardner; W. Haggard; H. Courtney; J. Wenke

Evaluation of biodegradable adjunctive therapy for extremity wound infection reduction

J. Jennings, S. Noel, B. Reves, K. Smith, S. Jackson, J. Bumgardner, W. Haggard, H. Courtney, J. Wenke

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Advances in surgical techniques, fixation devices, and hemorrhage control have improved functional outcomes in the field of extremity injury treatment. However, infection has become a primary concern, as it can lead to device failure, amputation, or death. Risk of infection may be lowered by local delivery of antibiotics, for which several carrier vehicles are available. Used as an adjunct to currently-used principles of debridement and lavage, local delivery systems have demonstrated efficacy, safety, and convenience for treatment of complex wounds. In this work, differences and modifications of various types of local antibiotic delivery systems are explored. Performance evaluations described are useful in the development of new carriers and in the selection of clinical therapies.

Original language	English (US)
Title of host publication	Medical Device Materials V - Proceedings of the Materials and Processes for Medical Devices Conference
Pages	117-122
Number of pages	6
State	Published - 2010
Externally published	Yes
Event	5th Materials and Processes for Medical Devices Conference, MPMD - Minneapolis, MN, United States Duration: Aug 10 2009 → Aug 12 2009

Publication series

Name	Medical Device Materials V - Proceedings of the Materials and Processes for Medical Devices Conference

Conference

Conference	5th Materials and Processes for Medical Devices Conference, MPMD
Country/Territory	United States
City	Minneapolis, MN
Period	8/10/09 → 8/12/09

ASJC Scopus subject areas

Biomedical Engineering
Materials Chemistry

Cite this

Jennings, J., Noel, S., Reves, B., Smith, K., Jackson, S., Bumgardner, J., Haggard, W., Courtney, H., & Wenke, J. (2010). Evaluation of biodegradable adjunctive therapy for extremity wound infection reduction. In Medical Device Materials V - Proceedings of the Materials and Processes for Medical Devices Conference (pp. 117-122). (Medical Device Materials V - Proceedings of the Materials and Processes for Medical Devices Conference).

Evaluation of biodegradable adjunctive therapy for extremity wound infection reduction. / Jennings, J.; Noel, S.; Reves, B. et al.
Medical Device Materials V - Proceedings of the Materials and Processes for Medical Devices Conference. 2010. p. 117-122 (Medical Device Materials V - Proceedings of the Materials and Processes for Medical Devices Conference).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Jennings, J, Noel, S, Reves, B, Smith, K, Jackson, S, Bumgardner, J, Haggard, W, Courtney, H & Wenke, J 2010, Evaluation of biodegradable adjunctive therapy for extremity wound infection reduction. in Medical Device Materials V - Proceedings of the Materials and Processes for Medical Devices Conference. Medical Device Materials V - Proceedings of the Materials and Processes for Medical Devices Conference, pp. 117-122, 5th Materials and Processes for Medical Devices Conference, MPMD, Minneapolis, MN, United States, 8/10/09.

Jennings J, Noel S, Reves B, Smith K, Jackson S, Bumgardner J et al. Evaluation of biodegradable adjunctive therapy for extremity wound infection reduction. In Medical Device Materials V - Proceedings of the Materials and Processes for Medical Devices Conference. 2010. p. 117-122. (Medical Device Materials V - Proceedings of the Materials and Processes for Medical Devices Conference).

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AU - Courtney, H.

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AB - Advances in surgical techniques, fixation devices, and hemorrhage control have improved functional outcomes in the field of extremity injury treatment. However, infection has become a primary concern, as it can lead to device failure, amputation, or death. Risk of infection may be lowered by local delivery of antibiotics, for which several carrier vehicles are available. Used as an adjunct to currently-used principles of debridement and lavage, local delivery systems have demonstrated efficacy, safety, and convenience for treatment of complex wounds. In this work, differences and modifications of various types of local antibiotic delivery systems are explored. Performance evaluations described are useful in the development of new carriers and in the selection of clinical therapies.

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Evaluation of biodegradable adjunctive therapy for extremity wound infection reduction

Abstract

Publication series

Conference

ASJC Scopus subject areas

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