Ethnic differences in heterotopic ossification following total hip arthroplasty

G. Davis; R. P. Patel; T. L. Tan; P. Alijanipour; T. U. Naik; J. Parvizi

doi:10.1302/0301-620X.98B6.36050

Ethnic differences in heterotopic ossification following total hip arthroplasty

G. Davis, R. P. Patel, T. L. Tan, P. Alijanipour, T. U. Naik, J. Parvizi

Research output: Contribution to journal › Article › peer-review

Abstract

Aims: We aimed to assess the influence of ethnicity on the incidence of heterotopic ossification (HO) after total hip arthroplasty (THA). Patients and Methods: We studied the six-month post-operative anteroposterior radiographs of 1449 consecutive primary THAs (1324 patients) and retrospectively graded them for the presence of HO, using the Brooker Classification. Results: Based on multivariate analysis, African-American ethnicity was an independent risk factor for HO formation following THA with an adjusted odds ratio (OR) of 2.6 (95% confidence interval (CI) 1.3 to 5.2, p = 0.007) for severe HO and 1.9 (95% CI 1.3 to 2.7, p < 0.001) for any grade of HO. Conclusion: Given the increased risk of HO formation, particularly high grade HO, and the potentially poorer outcomes associated with HO, it is important to consider using prophylaxis against HO in patients of African-American ethnicity undergoing THA.

Original language	English (US)
Pages (from-to)	761-766
Number of pages	6
Journal	Bone and Joint Journal
Volume	98-B
Issue number	6
DOIs	https://doi.org/10.1302/0301-620X.98B6.36050
State	Published - Jun 2016
Externally published	Yes

ASJC Scopus subject areas

General Medicine

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title = "Ethnic differences in heterotopic ossification following total hip arthroplasty",

abstract = "Aims: We aimed to assess the influence of ethnicity on the incidence of heterotopic ossification (HO) after total hip arthroplasty (THA). Patients and Methods: We studied the six-month post-operative anteroposterior radiographs of 1449 consecutive primary THAs (1324 patients) and retrospectively graded them for the presence of HO, using the Brooker Classification. Results: Based on multivariate analysis, African-American ethnicity was an independent risk factor for HO formation following THA with an adjusted odds ratio (OR) of 2.6 (95% confidence interval (CI) 1.3 to 5.2, p = 0.007) for severe HO and 1.9 (95% CI 1.3 to 2.7, p < 0.001) for any grade of HO. Conclusion: Given the increased risk of HO formation, particularly high grade HO, and the potentially poorer outcomes associated with HO, it is important to consider using prophylaxis against HO in patients of African-American ethnicity undergoing THA.",

author = "G. Davis and Patel, {R. P.} and Tan, {T. L.} and P. Alijanipour and Naik, {T. U.} and J. Parvizi",

note = "Publisher Copyright: {\textcopyright} 2016 The British Editorial Society of Bone & Joint Surgery.",

year = "2016",

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doi = "10.1302/0301-620X.98B6.36050",

language = "English (US)",

volume = "98-B",

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T1 - Ethnic differences in heterotopic ossification following total hip arthroplasty

AU - Davis, G.

AU - Patel, R. P.

AU - Tan, T. L.

AU - Alijanipour, P.

AU - Naik, T. U.

AU - Parvizi, J.

PY - 2016/6

Y1 - 2016/6

N2 - Aims: We aimed to assess the influence of ethnicity on the incidence of heterotopic ossification (HO) after total hip arthroplasty (THA). Patients and Methods: We studied the six-month post-operative anteroposterior radiographs of 1449 consecutive primary THAs (1324 patients) and retrospectively graded them for the presence of HO, using the Brooker Classification. Results: Based on multivariate analysis, African-American ethnicity was an independent risk factor for HO formation following THA with an adjusted odds ratio (OR) of 2.6 (95% confidence interval (CI) 1.3 to 5.2, p = 0.007) for severe HO and 1.9 (95% CI 1.3 to 2.7, p < 0.001) for any grade of HO. Conclusion: Given the increased risk of HO formation, particularly high grade HO, and the potentially poorer outcomes associated with HO, it is important to consider using prophylaxis against HO in patients of African-American ethnicity undergoing THA.

AB - Aims: We aimed to assess the influence of ethnicity on the incidence of heterotopic ossification (HO) after total hip arthroplasty (THA). Patients and Methods: We studied the six-month post-operative anteroposterior radiographs of 1449 consecutive primary THAs (1324 patients) and retrospectively graded them for the presence of HO, using the Brooker Classification. Results: Based on multivariate analysis, African-American ethnicity was an independent risk factor for HO formation following THA with an adjusted odds ratio (OR) of 2.6 (95% confidence interval (CI) 1.3 to 5.2, p = 0.007) for severe HO and 1.9 (95% CI 1.3 to 2.7, p < 0.001) for any grade of HO. Conclusion: Given the increased risk of HO formation, particularly high grade HO, and the potentially poorer outcomes associated with HO, it is important to consider using prophylaxis against HO in patients of African-American ethnicity undergoing THA.

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Ethnic differences in heterotopic ossification following total hip arthroplasty

Abstract

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