Epidemiology, evolution, and recent outbreaks of avian influenza virus in China

Shuo Su; Yuhai Bi; Gary Wong; Gregory C. Gray; George F. Gao; Shoujun Li

doi:10.1128/JVI.01034-15

Epidemiology, evolution, and recent outbreaks of avian influenza virus in China

Shuo Su, Yuhai Bi, Gary Wong, Gregory C. Gray, George F. Gao, Shoujun Li

Research output: Contribution to journal › Article › peer-review

Abstract

Novel reassortants of H7N9, H10N8, and H5N6 avian influenza viruses (AIVs) are currently circulating in China's poultry flocks, occasionally infecting humans and other mammals. Combined with the sometimes enzootic H5N1 and H9N2 strains, this cauldron of genetically diverse AIVs pose significant risks to public health. Here, we review the epidemiology, evolution, and recent outbreaks of AIVs in China, discuss reasons behind the recent increase in the emergence of novel AIVs, and identify warning signs which may point to the emergence of a potentially virulent and highly transmissible AIV to humans. This review will be useful to authorities who consider options for the detection and control of AIV transmission in animals and humans, with the goal of preventing future epidemics and pandemics.

Original language	English (US)
Pages (from-to)	8671-8676
Number of pages	6
Journal	Journal of virology
Volume	89
Issue number	17
DOIs	https://doi.org/10.1128/JVI.01034-15
State	Published - 2015
Externally published	Yes

ASJC Scopus subject areas

Microbiology
Immunology
Insect Science
Virology

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title = "Epidemiology, evolution, and recent outbreaks of avian influenza virus in China",

abstract = "Novel reassortants of H7N9, H10N8, and H5N6 avian influenza viruses (AIVs) are currently circulating in China's poultry flocks, occasionally infecting humans and other mammals. Combined with the sometimes enzootic H5N1 and H9N2 strains, this cauldron of genetically diverse AIVs pose significant risks to public health. Here, we review the epidemiology, evolution, and recent outbreaks of AIVs in China, discuss reasons behind the recent increase in the emergence of novel AIVs, and identify warning signs which may point to the emergence of a potentially virulent and highly transmissible AIV to humans. This review will be useful to authorities who consider options for the detection and control of AIV transmission in animals and humans, with the goal of preventing future epidemics and pandemics.",

author = "Shuo Su and Yuhai Bi and Gary Wong and Gray, {Gregory C.} and Gao, {George F.} and Shoujun Li",

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doi = "10.1128/JVI.01034-15",

language = "English (US)",

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AU - Su, Shuo

AU - Bi, Yuhai

AU - Wong, Gary

AU - Gray, Gregory C.

AU - Gao, George F.

AU - Li, Shoujun

PY - 2015

Y1 - 2015

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Epidemiology, evolution, and recent outbreaks of avian influenza virus in China

Abstract

ASJC Scopus subject areas

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