Epidemic alphaviruses: Ecology, emergence and outbreaks

Sasha Azar, Rafael K. Campos, Nicholas A. Bergren, Vidyleison N. Camargos, Shannan L. Rossi

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations


Over the past century, the emergence/reemergence of arthropod-borne zoonotic agents has been a growing public health concern. In particular, agents from the genus Alphavirus pose a significant risk to both animal and human health. Human alphaviral disease presents with either arthritogenic or encephalitic manifestations and is associated with significant morbidity and/or mortality. Unfortunately, there are presently no vaccines or antiviral measures approved for human use. The present review examines the ecology, epidemiology, disease, past outbreaks, and potential to cause contemporary outbreaks for several alphavirus pathogens.

Original languageEnglish (US)
Article number1167
Pages (from-to)1-35
Number of pages35
Issue number8
StatePublished - Aug 2020


  • Alphavirus
  • Enzootic
  • Epizootic
  • Mosquitoes
  • Outbreaks
  • Togaviridae

ASJC Scopus subject areas

  • Microbiology (medical)
  • Virology
  • Microbiology


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