Endoscopic ultrasound guided liver biopsy for parenchymal liver disease

Aun Raza Shah, Muhannad Al-Hanayneh, Monica Chowdhry, Mohammad Bilal, Shailendra Singh

Research output: Contribution to journalShort surveypeer-review

7 Scopus citations


Liver biopsy plays an essential role in the diagnosis, evaluation and management of a vast proportion of liver diseases. Conventionally, percutaneous and transjugular approaches have been used to obtain liver biopsies. Endoscopic ultrasound guided liver biopsy (EUS-LB) has emerged as a safe and effective alternate in the past two decades. EUS-LB carries a role in evaluation of both benign and malignant diseases of the liver. It can offer higher resolution imaging of the liver and can detect smaller lesions than computed tomography scan of the abdomen or ultrasound scans with the option for doppler assistance to reduce complications. Current evidence demonstrates the superiority of EUS-LB for a targeted approach of focal lesion and there is also evidence of less sampling variability in heterogeneous parenchymal pathologies. These advantages combined with an improved safety profile had led to the rapid progress in the development of new techniques, equipment and procedures for EUS-LB. We provide a comprehensive review of EUS-LB for parenchymal liver disease.

Original languageEnglish (US)
Pages (from-to)335-343
Number of pages9
JournalWorld Journal of Hepatology
Issue number4
StatePublished - Apr 1 2019


  • Endoscopic ultrasound
  • Endoscopic ultrasound guided liver biopsy
  • Liver biopsy
  • Liver disease

ASJC Scopus subject areas

  • Hepatology


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