Endoscopic treatment of biliary leakage with n-butyl-2 cyanoacrylate

Stefan Seewald; Stefan Groth; Parupudi V.J. Sriram; He Xikun; Thawatchai Akaraviputh; Gerardo Mendoza; Boris Brand; Uwe Seitz; Frank Thonke; Nib Soehendra

doi:10.1016/S0016-5107(02)70375-1

Endoscopic treatment of biliary leakage with n-butyl-2 cyanoacrylate

Stefan Seewald, Stefan Groth, Parupudi V.J. Sriram, He Xikun, Thawatchai Akaraviputh, Gerardo Mendoza, Boris Brand, Uwe Seitz, Frank Thonke, Nib Soehendra

Research output: Contribution to journal › Article › peer-review

71 Scopus citations

Abstract

Background: Biliary leakage is a problematic complication of hepatobiliary surgery. A novel alternative method is described that can obviate the need for reoperation for refractory biliary fistula. Methods: Nine patients with large biliary leaks unresponsive to endoscopic drainage underwent N-butyl-2-cyanoacrylate glue occlusion at ERCP. Results: In 7 patients, occlusion was successful with prompt control of the fistula in a single session, averting reoperation. In 1 patient there was a partial response and in another the treatment was unsuccessful. No procedure-related complication occurred over a median follow-up of 35 months (range: 1.6-160 months). Conclusion: N-butyl-2-cyanoacrylate glue occlusion is a safe and effective endoscopic method for control of refractory bile leaks that eliminates the need for surgical reintervention.

Original language	English (US)
Pages (from-to)	916-919
Number of pages	4
Journal	Gastrointestinal endoscopy
Volume	56
Issue number	6
DOIs	https://doi.org/10.1016/S0016-5107(02)70375-1
State	Published - Dec 2002
Externally published	Yes

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Gastroenterology

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10.1016/S0016-5107(02)70375-1

Cite this

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title = "Endoscopic treatment of biliary leakage with n-butyl-2 cyanoacrylate",

abstract = "Background: Biliary leakage is a problematic complication of hepatobiliary surgery. A novel alternative method is described that can obviate the need for reoperation for refractory biliary fistula. Methods: Nine patients with large biliary leaks unresponsive to endoscopic drainage underwent N-butyl-2-cyanoacrylate glue occlusion at ERCP. Results: In 7 patients, occlusion was successful with prompt control of the fistula in a single session, averting reoperation. In 1 patient there was a partial response and in another the treatment was unsuccessful. No procedure-related complication occurred over a median follow-up of 35 months (range: 1.6-160 months). Conclusion: N-butyl-2-cyanoacrylate glue occlusion is a safe and effective endoscopic method for control of refractory bile leaks that eliminates the need for surgical reintervention.",

author = "Stefan Seewald and Stefan Groth and Sriram, {Parupudi V.J.} and He Xikun and Thawatchai Akaraviputh and Gerardo Mendoza and Boris Brand and Uwe Seitz and Frank Thonke and Nib Soehendra",

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TY - JOUR

T1 - Endoscopic treatment of biliary leakage with n-butyl-2 cyanoacrylate

AU - Seewald, Stefan

AU - Groth, Stefan

AU - Sriram, Parupudi V.J.

AU - Xikun, He

AU - Akaraviputh, Thawatchai

AU - Mendoza, Gerardo

AU - Brand, Boris

AU - Seitz, Uwe

AU - Thonke, Frank

AU - Soehendra, Nib

PY - 2002/12

Y1 - 2002/12

N2 - Background: Biliary leakage is a problematic complication of hepatobiliary surgery. A novel alternative method is described that can obviate the need for reoperation for refractory biliary fistula. Methods: Nine patients with large biliary leaks unresponsive to endoscopic drainage underwent N-butyl-2-cyanoacrylate glue occlusion at ERCP. Results: In 7 patients, occlusion was successful with prompt control of the fistula in a single session, averting reoperation. In 1 patient there was a partial response and in another the treatment was unsuccessful. No procedure-related complication occurred over a median follow-up of 35 months (range: 1.6-160 months). Conclusion: N-butyl-2-cyanoacrylate glue occlusion is a safe and effective endoscopic method for control of refractory bile leaks that eliminates the need for surgical reintervention.

AB - Background: Biliary leakage is a problematic complication of hepatobiliary surgery. A novel alternative method is described that can obviate the need for reoperation for refractory biliary fistula. Methods: Nine patients with large biliary leaks unresponsive to endoscopic drainage underwent N-butyl-2-cyanoacrylate glue occlusion at ERCP. Results: In 7 patients, occlusion was successful with prompt control of the fistula in a single session, averting reoperation. In 1 patient there was a partial response and in another the treatment was unsuccessful. No procedure-related complication occurred over a median follow-up of 35 months (range: 1.6-160 months). Conclusion: N-butyl-2-cyanoacrylate glue occlusion is a safe and effective endoscopic method for control of refractory bile leaks that eliminates the need for surgical reintervention.

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Endoscopic treatment of biliary leakage with n-butyl-2 cyanoacrylate

Abstract

ASJC Scopus subject areas

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