Effects of glutathione depletors on post-ischemic reperfusion in rat brain

G. Martinez; M. L. Carnazza; A. Campisi; V. Sorrenti; C. Di Giacomo; J. R. Perez-Polo; A. Vanella

doi:10.1023/A:1021080321320

Effects of glutathione depletors on post-ischemic reperfusion in rat brain

G. Martinez, M. L. Carnazza, A. Campisi, V. Sorrenti, C. Di Giacomo, J. R. Perez-Polo, A. Vanella

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

The present paper reports the effects of GSH depletion (diethylmaleate induced) on partial cerebral ischemia and reperfusion for 7 and 20 days. Our results confirm that there is a paradoxical protective effect of the GSH- depletor and suggest an improved neuronal trophism induced by diethylmaleate treatment.

Original language	English (US)
Pages (from-to)	961-968
Number of pages	8
Journal	Neurochemical Research
Volume	23
Issue number	7
DOIs	https://doi.org/10.1023/A:1021080321320
State	Published - 1998
Externally published	Yes

Keywords

GSH-depletors
Ischemia
Reperfusion

ASJC Scopus subject areas

Biochemistry
Cellular and Molecular Neuroscience

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title = "Effects of glutathione depletors on post-ischemic reperfusion in rat brain",

abstract = "The present paper reports the effects of GSH depletion (diethylmaleate induced) on partial cerebral ischemia and reperfusion for 7 and 20 days. Our results confirm that there is a paradoxical protective effect of the GSH- depletor and suggest an improved neuronal trophism induced by diethylmaleate treatment.",

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AU - Martinez, G.

AU - Carnazza, M. L.

AU - Campisi, A.

AU - Sorrenti, V.

AU - Di Giacomo, C.

AU - Perez-Polo, J. R.

AU - Vanella, A.

PY - 1998

Y1 - 1998

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AB - The present paper reports the effects of GSH depletion (diethylmaleate induced) on partial cerebral ischemia and reperfusion for 7 and 20 days. Our results confirm that there is a paradoxical protective effect of the GSH- depletor and suggest an improved neuronal trophism induced by diethylmaleate treatment.

KW - GSH-depletors

KW - Ischemia

KW - Reperfusion

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Effects of glutathione depletors on post-ischemic reperfusion in rat brain

Abstract

Keywords

ASJC Scopus subject areas

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